Investigating the atmospheric pressure plasma jet modification of a photo-crosslinkable hydrogel
Visualitza/Obre
10.1016/j.polymer.2020.122308
Inclou dades d'ús des de 2022
Cita com:
hdl:2117/187294
Realitzat a/ambLe Mans Université
Tipus de documentArticle
Data publicació2020-03-27
EditorElsevier
Condicions d'accésAccés obert
Llevat que s'hi indiqui el contrari, els
continguts d'aquesta obra estan subjectes a la llicència de Creative Commons
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Reconeixement-NoComercial-SenseObraDerivada 3.0 Espanya
ProjecteAPACHE - Atmospheric Pressure plAsma meets biomaterials for bone Cancer HEaling (EC-H2020-714793)
Abstract
Atmospheric pressure plasma jets (APPJ) have great potential in wound healing, bacterial disinfection and in cancer therapy. Recent studies pointed out that hydrogels can be used as screens during APPJ treatment, or even be used as reservoirs for reactive oxygen and nitrogen species generated by APPJ in liquids. Thus, novel applications are emerging for hydrogels which deserve fundamental exploration of the possible modifications undergone by the polymers in solution due to the reactivity with plasmas. Here we investigate the possible modifications occurred by APPJ treatment of an amphiphilic poly(ethylene oxide)-based triblock copolymer (tPEO) photo-crosslinkable hydrogel. While APPJ treatments lead to a certain degradation of the self-assembly of the polymeric chains at low concentrations (<2 g/L), at the higher concentrations required to form a hydrogel (>2 g/L), the polymeric chains are unaffected by APPJ and the hydrogel forming ability is kept. APPJ treatments induced a pre-crosslinking of the network with an increase of the mechanical properties of the hydrogel. Overall, the small modifications induced allow thinking of polymer solutions with hydrogel forming ability a new platform for several applications related to plasma medicine, and thus, with potential in different therapies.
CitacióHamouda, I. [et al.]. Investigating the atmospheric pressure plasma jet modification of a photo-crosslinkable hydrogel. "Polymer", 27 Març 2020, vol. 192, p. 122308:1-122308:9.
ISSN0032-3861
Versió de l'editorhttps://www.sciencedirect.com/science/article/pii/S0032386120301464
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Proofs Hamouda Tpoe.pdf | Article Open access | 8,168Mb | Visualitza/Obre |