Doctorat en Bioinformàtica

Recent Submissions

  • Effect of sodium valproate on the conformational stability of the visual G Protein-coupled receptor rhodopsin 

    Razzaghi, Neda; Fernández González, Pol; Mas Sánchez, Aina; Vila i Julià, Guillem; Pérez González, Juan Jesús; Garriga Solé, Pere (2021-05-19)
    Article
    Open Access
    Rhodopsin is the G protein-coupled receptor of rod photoreceptor cells that mediates vertebrate vision at low light intensities. Mutations in rhodopsin cause inherited retinal degenerative diseases such as retinitis ...

  • Lower Locus Coeruleus MRI intensity in patients with late-life major depression 

    Guinea Izquierdo, Andrés; Giménez Navarro, Mónica; Martínez Zalacaín, Ignacio; Cerro San Ildefonso, Inés del; Canal Noguer, Pol; Blasco, Gerard; Soriano Mas, Carles; Gascón Gutiérrez, Jordi; Reñé Ramírez, Ramon; Rico Pons, Immaculada; Camins Simó, Àngel; Aguilera Grijalvo, Carlos (2021-02-16)
    Article
    Open Access
    Background: The locus coeruleus (LC) is the major noradrenergic source in the central nervous system. Structural alterations in the LC contribute to the pathophysiology of different neuropsychiatric disorders, which may ...

  • A parallel dynamic asynchronous framework for uncertainty quantification by hierarchical Monte Carlo algorithms 

    Tosi, Riccardo; Amela Milian, Ramon; Badia Sala, Rosa Maria; Rossi, Riccardo (Springer Nature, 2021-09-13)
    Article
    Open Access
    The necessity of dealing with uncertainties is growing in many different fields of science and engineering. Due to the constant development of computational capabilities, current solvers must satisfy both statistical ...

  • ExaQUte: D5.2 Release of ExaQUte MLMC Python engine 

    Amela Milian, Ramon; Ayoul-Guilmard, Quentin; Ganesh, Sundar; Tosi, Riccardo; Badia Sala, Rosa Maria; Nobile, Fabio; Rossi, Riccardo (2019-05-30)
    Research report
    Open Access
    In this deliverable, the ExaQUte xmc library is introduced. This report is meant to serve as a supplement to the publicly release of the library. In the following sections, the ExaQUte xmc library is described along with ...

  • ExaQUte: D1.2 First release of the softwares 

    Tosi, Riccardo; Amela Milian, Ramon; Núñez Corbacho, Marc; Roig Pina, Carlos Alejandro; Badia Sala, Rosa Maria; Rossi, Riccardo (2019-05-30)
    Research report
    Open Access
    This deliverable presents the software release of the Kratos Multiphysics software [3], ”a framework for building parallel, multi-disciplinary simulation software, aiming at modularity, extensibility, and high performance. ...

  • ExaQUte: D4.2 Profiling report of the partner’s tools, complete with performance suggestions 

    Amela Milian, Ramon; Badia Sala, Rosa Maria; Böhm, Stanislav; Tosi, Riccardo; Rossi, Riccardo (2019-05-30)
    Research report
    Open Access
    This deliverable focuses on the proling activities developed in the project with the partner's applications. To perform this proling activities, a couple of benchmarks were dened in collaboration with WP5. The rst benchmark ...

  • Probabilistic graphlets capture biological function in probabilistic molecular networks 

    Doria Belenguer, Sergio; Youssef, Markus Kirolos; Böttcher, René; Malod-Dognin, Noël; Pržulj, Nataša (Oxford University Press, 2020-12-29)
    Article
    Open Access
    Motivation: Molecular interactions have been successfully modeled and analyzed as networks, where nodes represent molecules and edges represent the interactions between them. These networks revealed that molecules with ...

  • The impact of non-additive genetic associations on age-related complex diseases 

    Guindo Martínez, Marta; Amela Milian, Ramon; Bonàs Guarch, Silvia; Puiggros Maldonado, Montserrat; Salvoro, Cecilia; Miguel Escalada, Irene; Sánchez Castaño, Friman; Ramón Cortés, Cristian; Badia Sala, Rosa Maria; Ejarque Artigas, Jorge; Mercader Bigas, Josep Maria; Torrents Rodas, David (2021-04-23)
    Article
    Open Access
    Genome-wide association studies (GWAS) are not fully comprehensive, as current strategies typically test only the additive model, exclude the X chromosome, and use only one reference panel for genotype imputation. We ...

  • AutoParallel: Automatic parallelisation and distributed execution of affine loop nests in Python 

    Ramón Cortés, Cristian; Amela Milian, Ramon; Ejarque Artigas, Jorge; Clauss, Philippe; Badia Sala, Rosa Maria (Sage, 2020)
    Article
    Open Access
    The last improvements in programming languages and models have focused on simplicity and abstraction; leading Python to the top of the list of the programming languages. However, there is still room for improvement when ...

  • Efficient development of high performance data analytics in Python 

    Álvarez Cid-Fuentes, Javier; Alvarez, Pol; Amela Milian, Ramon; Ishii, Kuninori; Morizawa, Rafael K.; Badia Sala, Rosa Maria (Elsevier, 2020-10)
    Article
    Open Access
    Our society is generating an increasing amount of data at an unprecedented scale, variety, and speed. This also applies to numerous research areas, such as genomics, high energy physics, and astronomy, for which large-scale ...

  • Executing linear algebra kernels in heterogeneous distributed infrastructures with PyCOMPSs 

    Amela Milian, Ramon; Ramon-cortés Vilarrodona, Cristian; Ejarque, Jorge; Conejero, Javier; Badia Sala, Rosa Maria (EDP Open, 2018-10-24)
    Article
    Open Access
    Python is a popular programming language due to the simplicity of its syntax, while still achieving a good performance even being an interpreted language. The adoption from multiple scientific communities has evolved in ...

  • Enabling Python to execute efficiently in heterogeneous distributed infrastructures with PyCOMPSs 

    Amela Milian, Ramon; Ramón Cortés, Cristian; Ejarque, Jorge; Conejero Bañón, Javier; Badia Sala, Rosa Maria (Association for Computing Machinery (ACM), 2017-11)
    Conference lecture
    Open Access
    Python has been adopted as programming language by a large number of scientific communities. Additionally to the easy programming interface, the large number of libraries and modules that have been made available by a large ...