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  • XV International Conference on Computational Plasticity: fundamentals and applications (COMPLAS 2019), Barcelona, 3-5 September, 2019
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Multiscale modelling of liver perfusion

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hdl:2117/181614

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Rohan, Eduard
Turjanicová, Jana
Lukes, Vladimír
Document typeConference report
Defense date2019
PublisherCIMNE
Rights accessOpen Access
All rights reserved. This work is protected by the corresponding intellectual and industrial property rights. Without prejudice to any existing legal exemptions, reproduction, distribution, public communication or transformation of this work are prohibited without permission of the copyright holder
Abstract
We compare two homogenized models of the microcirculation which rely on different assumptions. The first model has been derived by the homogenization of the mesoscopic structure with the double-porosity medium represented by the Biot model with large contrasts in the permeability coefficients constituting the Darcy law. The newly developed so-called Biot-Darcy-Brinkman (BDB) model is described in the paper; it arises from a two-stage homogenization of the fluid-structure interaction problem which requires geometric representations of the sinusoidal and the inter-lobular vasculatures associated with venous compartments, the portal and the hepatic veins. An illustrative example shows a good correspondence between the two models.
URIhttp://hdl.handle.net/2117/181614
ISBN978-84-949194-7-3
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  • COMPLAS - XV International Conference on Computational Plasticity: fundamentals and applications (COMPLAS 2019), Barcelona, 3-5 September, 2019 [55]
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