Multiscale modelling of liver perfusion

Cita com:
hdl:2117/181614
Document typeConference report
Defense date2019
PublisherCIMNE
Rights accessOpen Access
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Abstract
We compare two homogenized models of the microcirculation which rely on different assumptions. The first model has been derived by the homogenization of the mesoscopic structure with the double-porosity medium represented by the Biot model with large contrasts in the permeability coefficients constituting the Darcy law. The newly developed so-called Biot-Darcy-Brinkman (BDB) model is described in the paper; it arises from a two-stage homogenization of the fluid-structure interaction problem which requires geometric representations of the sinusoidal and the inter-lobular vasculatures associated with venous compartments, the portal and the hepatic veins. An illustrative example shows a good correspondence between the two models.
ISBN978-84-949194-7-3
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