Ir al contenido (pulsa Retorno)

Universitat Politècnica de Catalunya

    • Català
    • Castellano
    • English
    • LoginRegisterLog in (no UPC users)
  • mailContact Us
  • world English 
    • Català
    • Castellano
    • English
  • userLogin   
      LoginRegisterLog in (no UPC users)

UPCommons. Global access to UPC knowledge

Banner header
69.147 UPC E-Prints
You are here:
View Item 
  •   DSpace Home
  • E-prints
  • Departaments
  • Departament de Ciència i Enginyeria de Materials
  • Articles de revista
  • View Item
  •   DSpace Home
  • E-prints
  • Departaments
  • Departament de Ciència i Enginyeria de Materials
  • Articles de revista
  • View Item
JavaScript is disabled for your browser. Some features of this site may not work without it.

Antimicrobial PHAs coatings for solid and porous tantalum implants

Thumbnail
View/Open
2019_Antimicrobial PHAs coatings for solid and porous Tantalum implants.pdf (1,500Mb)
2019_Antimicrobial PHAs coatings for solid and porous Tantalum implants.pdf (1,500Mb)
 
10.1016/j.colsurfb.2019.06.047
 
  View UPCommons Usage Statistics
  LA Referencia / Recolecta stats
Includes usage data since 2022
Cita com:
hdl:2117/177254

Show full item record
Rodríguez Contreras, Alejandra MaríaMés informacióMés informació
Guillem Martí, JordiMés informacióMés informacióMés informació
Manero Planella, José MaríaMés informacióMés informacióMés informació
Rupérez de Gracia, ElisaMés informacióMés informacióMés informació
Document typeArticle
Defense date2019-10-01
Rights accessOpen Access
Attribution-NonCommercial-NoDerivs 3.0 Spain
This work is protected by the corresponding intellectual and industrial property rights. Except where otherwise noted, its contents are licensed under a Creative Commons license : Attribution-NonCommercial-NoDerivs 3.0 Spain
Abstract
Biomaterial-associated infections (BAI) are the major cause of failure of indwelling medical devices. The risk of BAI can end dramatically in the surgical removal of the affected device. Therefore, a major effort must be undertaken to guarantee the permanence of the implant. In this regard, we have developed antimicrobial coatings for tantalum (Ta) implants, using polyhydroxyalkanoates (PHAs) as matrices for carrying an active principle. The dip-coating technique was successfully used for covering solid Ta discs. An original PHA emulsion flow process was developed for the coating of porous Ta structures, specially for the inner surfaces. The complete characterization of the biopolymer coatings, their antibacterial properties, toxicity and biointegration were analyzed. Thus, non-toxic, well-biointegrated homogeneous biopolymer coatings were attained, which showed antibacterial properties. By using biodegradable PHAs, the resulting drug delivery system assured the protection of Ta against bacterial infections for a period of time.
CitationRodriguez, A. [et al.]. Antimicrobial PHAs coatings for solid and porous tantalum implants. "Colloids and Surfaces B: Biointerfaces", 1 Octubre 2019, vol. 182, p. 110317:1-110317: 9. 
URIhttp://hdl.handle.net/2117/177254
DOI10.1016/j.colsurfb.2019.06.047
ISSN1873-4367
Publisher versionhttps://www.sciencedirect.com/science/article/pii/S0927776519304539
Collections
  • Departament de Ciència i Enginyeria de Materials - Articles de revista [914]
  • BBT - Grup de recerca en Biomaterials, Biomecànica i Enginyeria de Teixits - Articles de revista [480]
  View UPCommons Usage Statistics

Show full item record

FilesDescriptionSizeFormatView
2019_Antimicrob ... rous Tantalum implants.pdf1,500MbPDFView/Open
2019_Antimicrob ... rous Tantalum implants.pdf1,500MbPDFView/Open

Browse

This CollectionBy Issue DateAuthorsOther contributionsTitlesSubjectsThis repositoryCommunities & CollectionsBy Issue DateAuthorsOther contributionsTitlesSubjects

© UPC Obrir en finestra nova . Servei de Biblioteques, Publicacions i Arxius

info.biblioteques@upc.edu

  • About This Repository
  • Metadata under:Metadata under CC0
  • Contact Us
  • Send Feedback
  • Privacy Settings
  • Inici de la pàgina