Changes in Creatine Kinase, High-sensitivity troponin T, ST2, NT-proBNP and Bioimpedance Mesurements in Trekkers and Professional Alpinist at Everest 2017
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TFG memoria final Roger Marginet i Assens.pdf (2,336Mb) (Accés restringit)
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Correu electrònic de l'autorroger.marginethotmail.com
Tipus de documentTreball Final de Grau
Data2018-06-28
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Abstract
The World Health Organization (WHO) estimates that over 35 million people go above 3,000m
every year for various reasons, which makes it necessary to have a better understanding of the
physiological reactions due to altitude. Furthermore, the number of climbers who go above the 3,000m
has been growing worldwide, and in the last two decades the number of successful Everest summits
has doubled [1]–[3].
This study quantifies the myocardial and skeletal cell injury caused by climbing mount Everest and
the conditions and biomarkers that must be analysed before attempting it. Therefore, the physiological
measurements of resistance and reactance of whole body measurements will be analysed, as well as
biochemical concentrations of muscular enzymes, electrolytes and cardiac biomarkers. The aim of this
study is to determine which biomarkers must be analysed before attempting the summit as well as to
understand how the body behaves while ascending to extreme altitude and how that changes with
race. This information could be useful to athletes who exercise at high altitude, travellers or to the
scientific community in general.
After the statistical analysis of marathon data before the Everest ascension it was seen that the
biomarkers that must be analysed are the following: concentrations of muscular enzymes (CK),
electrolytes (Mg, K) and cardiac biomarkers (Hs-cTnT, ST2, NT-proBNP). The Everest measurements of
bioimpedance have stated that there is a clear physiological change between basal measurements at
0m and the measurements at base camp, 5364m. However there doesn’t seem to be a clear change
after reaching camp C4, 8000m, from base camp and back or between alpinist nor Sherpas, even if the
latter ones seem to fare better than alpinists.
MatèriesAltitude, Influence of, Sports -- Physiological aspects, Heart beat -- Measurement, Esports -- Aspectes fisiològics, Altituds, Marcadors bioquímics, Cor -- Batecs -- Mesurament
TitulacióGRAU EN ENGINYERIA BIOMÈDICA (Pla 2009)
Fitxers | Descripció | Mida | Format | Visualitza |
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TFG memoria final Roger Marginet i Assens.pdf | 2,336Mb | Accés restringit |