Mostra el registre d'ítem simple

dc.contributor.authorLuraghi, Giulia
dc.contributor.authorMigliavacca, Francesco
dc.contributor.authorGarcía González, Alberto
dc.contributor.authorChiastra, Claudio
dc.contributor.authorRossi, Alexia
dc.contributor.authorCao, Davide
dc.contributor.authorStefanini, Giulio
dc.contributor.authorRodríguez Matas, José Félix
dc.contributor.otherUniversitat Politècnica de Catalunya. Departament d'Enginyeria Civil i Ambiental
dc.date.accessioned2019-11-25T08:55:31Z
dc.date.available2020-09-01T00:31:09Z
dc.date.issued2019-09-01
dc.identifier.citationLuraghi, G. [et al.]. On the modeling of patient-specific transcatheter aortic valve replacement: a fluid–structure interaction approach. "Cardiovascular engineering and technology", 1 Setembre 2019, vol. 10, núm. 3, p. 437-455.
dc.identifier.issn1869-408X
dc.identifier.urihttp://hdl.handle.net/2117/172992
dc.descriptionThis is a post-peer-review, pre-copyedit version of an article published in Cardiovascular engineering and technology. The final authenticated version is available online at: http://dx.doi.org/10.1007/s13239-019-00427-0
dc.description.abstractPurpose Transcatheter aortic valve replacement (TAVR) is a minimally invasive treatment for high-risk patients with aortic diseases. Despite its increasing use, many influential factors are still to be understood and require continuous investigation. The best numerical approach capable of reproducing both the valves mechanics and the hemodynamics is the fluid–structure interaction (FSI) modeling. The aim of this work is the development of a patient-specific FSI methodology able to model the implantation phase as well as the valve working conditions during cardiac cycles. Methods The patient-specific domain, which included the aortic root, native valve and calcifications, was reconstructed from CT images, while the CAD model of the device, metallic frame and pericardium, was drawn from literature data. Ventricular and aortic pressure waveforms, derived from the patient’s data, were used as boundary conditions. The proposed method was applied to two real clinical cases, which presented different outcomes in terms of paravalvular leakage (PVL), the main complication after TAVR. Results The results confirmed the clinical prognosis of mild and moderate PVL with coherent values of regurgitant volume and effective regurgitant orifice area. Moreover, the final release configuration of the device and the velocity field were compared with postoperative CT scans and Doppler traces showing a good qualitative and quantitative matching. Conclusion In conclusion, the development of realistic and accurate FSI patient-specific models can be used as a support for clinical decisions before the implantation.
dc.format.extent19 p.
dc.language.isoeng
dc.publisherSpringer
dc.subjectÀrees temàtiques de la UPC::Matemàtiques i estadística::Anàlisi numèrica
dc.subjectÀrees temàtiques de la UPC::Matemàtiques i estadística::Investigació operativa::Programació matemàtica
dc.subject.lcshNumerical analysis
dc.subject.lcshNumerical analysis--Simulation methods
dc.subject.otherTranscatheter aortic valve replacement (TAVR)
dc.subject.otherTranscatheter aortic valve implantation (TAVI)
dc.subject.otherFluid–structure interaction simulation (FSI)
dc.subject.otherAortic valve
dc.subject.otherPatient-specific numerical model
dc.subject.otherFinite-element analysis (FE)
dc.titleOn the modeling of patient-specific transcatheter aortic valve replacement: a fluid–structure interaction approach
dc.typeArticle
dc.subject.lemacAnàlisi numèrica
dc.subject.lemacAnàlisi numèrica
dc.contributor.groupUniversitat Politècnica de Catalunya. LACÀN - Mètodes Numèrics en Ciències Aplicades i Enginyeria
dc.identifier.doi10.1007/s13239-019-00427-0
dc.description.peerreviewedPeer Reviewed
dc.subject.amsClassificació AMS::65 Numerical analysis::65K Mathematical programming, optimization and variational techniques
dc.subject.amsClassificació AMS::65 Numerical analysis::65C Probabilistic methods, simulation and stochastic differential equations
dc.relation.publisherversionhttps://link.springer.com/article/10.1007/s13239-019-00427-0
dc.rights.accessOpen Access
local.identifier.drac25734690
dc.description.versionPostprint (author's final draft)
local.citation.authorLuraghi, G.; Migliavacca, F.; Garcia, A.; Chiastra, C.; Rossi, A.; Cao, D.; Stefanini, G.; Rodríguez, J.
local.citation.publicationNameCardiovascular engineering and technology
local.citation.volume10
local.citation.number3
local.citation.startingPage437
local.citation.endingPage455


Fitxers d'aquest items

Thumbnail

Aquest ítem apareix a les col·leccions següents

Mostra el registre d'ítem simple