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dc.contributorGarcía Torres, José Manuel
dc.contributorEspañol Pons, Montserrat
dc.contributor.authorPerez Reyes, Daniel
dc.contributor.otherUniversitat Politècnica de Catalunya. Departament de Ciència dels Materials i Enginyeria Metal·lúrgica
dc.date.accessioned2019-11-08T19:31:35Z
dc.date.available2019-11-08T19:31:35Z
dc.date.issued2019-07-08
dc.identifier.urihttp://hdl.handle.net/2117/172011
dc.description.abstractTissue engineering is an emerging technology whose efforts are aimed towards repairing and regenerating injured tissues by developing bioactive scaffolds. Recently, scaffolds made of hydrogels have become interesting candidates for tissue engineering due to their tunable structures that allow to obtain constructs with a wide range of properties. However, incorporating cells into them and allowing cell proliferation and differentiation has been a challenge for tissue engineers in the past years. In this context, the aim of this project was to develop biocompatible bioinks capable of forming self-supportive 3D scaffold able to host cells. To achieve this challenge, different sets of bioinks were tested. Firstly, different general formulations based on alginate pluronic and gelatin were tested. In a second group of formulations, pluronic was removed to assess cell viability. The last group of formulations was based on a mixture of alginate, collagen and hydroxyapatite nanoparticles, focusing on a putative application in bone tissue. All formulations were characterized in terms of morphology, degradation and cell viability. In conclusion, gelatin-containing bioinks tended to be weaker than collagen-hydroxyapatite ones. However, there was no significant difference in cell viability studies between all of them
dc.language.isoeng
dc.publisherUniversitat Politècnica de Catalunya
dc.rightsAttribution 3.0 Spain
dc.rights.urihttp://creativecommons.org/licenses/by-sa/3.0/es/
dc.subjectÀrees temàtiques de la UPC::Enginyeria química
dc.subject.lcshTissue engineering
dc.subject.lcshThree-dimensional printing
dc.subject.lcshColloids
dc.subject.lcshTissue scaffolds
dc.subject.otherBone tissue engineering
dc.subject.otherhydrogels
dc.subject.otheralginate
dc.subject.othergelatin
dc.subject.othercollagen
dc.subject.otherhydroxyapatite
dc.subject.other3D printing
dc.subject.otherscaffold
dc.title3D printed hydrogel-based scaffolds for tissue regeneration
dc.typeMaster thesis
dc.subject.lemacEnginyeria de teixits
dc.subject.lemacImpressió 3D
dc.subject.lemacCol·loides
dc.subject.lemacTeixits -- Bastides
dc.identifier.slugPRISMA-146304
dc.rights.accessOpen Access
dc.date.updated2019-10-28T09:49:41Z
dc.audience.educationlevelMàster
dc.audience.mediatorEscola d'Enginyeria de Barcelona Est


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