Ir al contenido (pulsa Retorno)

Universitat Politècnica de Catalunya

    • Català
    • Castellano
    • English
    • LoginRegisterLog in (no UPC users)
  • mailContact Us
  • world English 
    • Català
    • Castellano
    • English
  • userLogin   
      LoginRegisterLog in (no UPC users)

UPCommons. Global access to UPC knowledge

Banner header
68.885 UPC E-Prints
You are here:
View Item 
  •   DSpace Home
  • E-prints
  • Grups de recerca
  • CDAL - Centre de Disseny d'Aliatges Lleugers i Tractaments de Superfície
  • Articles de revista
  • View Item
  •   DSpace Home
  • E-prints
  • Grups de recerca
  • CDAL - Centre de Disseny d'Aliatges Lleugers i Tractaments de Superfície
  • Articles de revista
  • View Item
JavaScript is disabled for your browser. Some features of this site may not work without it.

A low elastic modulus Ti-Nb-Hf alloy bioactivated with an elastin-like

Thumbnail
View/Open
A low elastic modulus Ti-Nb-Hf alloy bioactivated with an elastin-like.pdf (642,4Kb) (Restricted access)   Request copy 

Què és aquest botó?

Aquest botó permet demanar una còpia d'un document restringit a l'autor. Es mostra quan:

  • Disposem del correu electrònic de l'autor
  • El document té una mida inferior a 20 Mb
  • Es tracta d'un document d'accés restringit per decisió de l'autor o d'un document d'accés restringit per política de l'editorial
 
10.1002/jbm.a.34388
 
  View UPCommons Usage Statistics
  LA Referencia / Recolecta stats
Includes usage data since 2022
Cita com:
hdl:2117/17124

Show full item record
González, Marta
Salvagni, Emiliano
Rodríguez Cabello, J.C.
Rupérez de Gracia, ElisaMés informacióMés informacióMés informació
Gil Mur, Francisco JavierMés informacióMés informacióMés informació
Manero Planella, José MaríaMés informacióMés informacióMés informació
Peña, Javier
CovenanteeUniversidad de Valladolid
Document typeArticle
Defense date2012
Rights accessRestricted access - publisher's policy
Attribution-NonCommercial-NoDerivs 3.0 Spain
This work is protected by the corresponding intellectual and industrial property rights. Except where otherwise noted, its contents are licensed under a Creative Commons license : Attribution-NonCommercial-NoDerivs 3.0 Spain
Abstract
b-type titanium alloys with low Young’s modulus are desirable to reduce stress shielding effect and enhance bone remodeling for implants used to substitute failed hard tissue. For biomaterials application, the surface bioactivity is necessary to achieve optimal osseointegration. In the previous work, the low elastic modulus (43 GPa) Ti-25Nb-16Hf (wt %) alloy was mechanically and microstructurally characterized. In the present work, the biological behavior of Ti-25Nb- 16Hf was studied. The biological response was improved by surface modification. The metal surface was modified by oxygen plasma and subsequently silanized with 3-chloropropyl (triethoxy)silane for covalent immobilization of the elastin-like polymer. The elastin-like polymer employed exhibits RGD bioactive motives inspired to the extracellular matrix in order to improve cell adhesion and spreading. Upon modification, the achieved surface presented different physical and chemical properties, such as surface energy and chemical composition. Subsequently, osteoblast adhesion, cell numbers, and differentiation studies were performed to correlate surface properties and cell response. The general tendency was that the higher surface energy the higher cell adhesion. Furthermore, cell culture and immunofluorescence microscopy images demonstrated that RGD-modified surfaces improved adhesion and spreading of the osteoblast cell type.
CitationGonzález, M. [et al.]. A low elastic modulus Ti-Nb-Hf alloy bioactivated with an elastin-like. "Journal of biomedical materials research. Part A", 2012, vol. 00A, p. 000. 
URIhttp://hdl.handle.net/2117/17124
DOI10.1002/jbm.a.34388
ISSN1549-3296
Collections
  • CDAL - Centre de Disseny d'Aliatges Lleugers i Tractaments de Superfície - Articles de revista [27]
  • Departament de Ciència dels Materials i Enginyeria Metal·lúrgica - Articles de revista [960]
  • BBT - Grup de recerca en Biomaterials, Biomecànica i Enginyeria de Teixits - Articles de revista [479]
  View UPCommons Usage Statistics

Show full item record

FilesDescriptionSizeFormatView
A low elastic m ... d with an elastin-like.pdfBlocked642,4KbPDFRestricted access

Browse

This CollectionBy Issue DateAuthorsOther contributionsTitlesSubjectsThis repositoryCommunities & CollectionsBy Issue DateAuthorsOther contributionsTitlesSubjects

© UPC Obrir en finestra nova . Servei de Biblioteques, Publicacions i Arxius

info.biblioteques@upc.edu

  • About This Repository
  • Metadata under:Metadata under CC0
  • Contact Us
  • Send Feedback
  • Privacy Settings
  • Inici de la pàgina