Show simple item record

dc.contributor.authorMartí Gelabert, Meritxell
dc.contributor.authorMartínez, Vanessa
dc.contributor.authorLis Arias, Manuel José
dc.contributor.authorCoderch Negra, Luisa
dc.contributor.otherUniversitat Politècnica de Catalunya. Departament d'Enginyeria Química
dc.date.accessioned2019-07-17T10:15:06Z
dc.date.issued2019-06-24
dc.identifier.citationMartí, M. [et al.]. Mathematical models for drug delivery from textile. "Journal of Industrial Textiles", 24 Juny 2019.
dc.identifier.issn1528-0837
dc.identifier.urihttp://hdl.handle.net/2117/166363
dc.description.abstractGallic acid was microencapsulated in poly-¿-caprolactone by the solvent evaporation method and was applied onto biofunctional textile substrates, cotton, and polyamide fabrics using a finishing process. A higher content of microspheres on polyamide was obtained due to the more hydrophobic character of polyamide. Drug release in physiological serum was carried out with treated fabrics submerged into a thermostatized vessel at semi-infinite bath conditions. The kinetic study carried out allowed the determination of the drug-delivery behavior for all systems in the medium. The results showed that the hydrophobicity and affinity of textiles and gallic acid influenced the release mechanism. For cotton, a clear Fickian diffusion was obtained; for polyamide, the diffusion was anomalous. However, no differences were found in the global mass transport. The model could address the need of the medical and health sector for assessing the theoretical amount of drug released from biofunctional textile
dc.language.isoeng
dc.rightsAttribution-NonCommercial 3.0 Spain
dc.rights.urihttp://creativecommons.org/licenses/by-nc/3.0/es/
dc.subjectÀrees temàtiques de la UPC::Enginyeria tèxtil::Teixits::Teixits mèdics
dc.subject.lcshMicroencapsulation
dc.subject.lcshDrug delivery systems
dc.subject.lcshMicrospheres
dc.subject.lcshTextile fibers--Technological innovations
dc.subject.lcshTextile chemistry
dc.subject.otherPoly-¿-caprolactone
dc.subject.otherMicrospheres
dc.subject.otherBiofunctional textile
dc.subject.otherDrug delivery
dc.subject.otherModellization
dc.titleMathematical models for drug delivery from textile
dc.typeArticle
dc.subject.lemacMicroencapsulació
dc.subject.lemacTeixits i tèxtils -- Innovacions tecnològiques
dc.subject.lemacMedicaments -- Modes d'administració
dc.subject.lemacQuímica tèxtil
dc.contributor.groupUniversitat Politècnica de Catalunya. POLQUITEX - Materials Polimérics i Química Téxtil
dc.identifier.doi10.1177/1528083719858769
dc.relation.publisherversionhttps://journals.sagepub.com/doi/abs/10.1177/1528083719858769
dc.rights.accessRestricted access - publisher's policy
drac.iddocument25401327
dc.description.versionPostprint (author's final draft)
dc.date.lift2020-06
upcommons.citation.authorMartí, M.; Martínez, V.; Lis, M.; Coderch, L.
upcommons.citation.publishedtrue
upcommons.citation.publicationNameJournal of Industrial Textiles


Files in this item

Thumbnail

This item appears in the following Collection(s)

Show simple item record

Except where otherwise noted, content on this work is licensed under a Creative Commons license: Attribution-NonCommercial 3.0 Spain