Novel estimation of the electrical bioimpedance using the local polynomial method. Application to in vivo real-time myocardium tissue impedance characterization during the cardiac cycle
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hdl:2117/16062
Document typeArticle
Defense date2011-11-18
Rights accessRestricted access - publisher's policy
Abstract
Classicalmeasurements ofmyocardium tissue electrical impedance for characterizing the morphology of myocardium cells, as well as cell membranes integrity and intra/extra cellular spaces, are based on the frequency-sweep electrical impedance
spectroscopy (EIS) technique. In contrast to the frequency-sweep EIS approach, measuring with broadband signals, i.e., multisine
excitations, enables to collect, simultaneously, multiple myocardium
tissue impedance data in a short measuring time. However, reducing the measuring time makes the measurements to be prone to the influence of the transients introduced by noise and the dynamic time-varying properties of tissue. This paper
presents a novel approach for the impedance-frequency-response estimation based on the local polynomial method (LPM). The
fast LPM version presented rejects the leakage error’s influence on the impedance frequency response when measuring electrical
bioimpedance in a short time. The theory is supported by a set of validation measurements. Novel preliminary experimental results obtained from real-time in vivo healthy myocardium tissue impedance characterization within the cardiac cycle using multisine excitation are reported.
CitationSánchez, B. [et al.]. Novel estimation of the electrical bioimpedance using the local polynomial method. Application to in vivo real-time myocardium tissue impedance characterization during the cardiac cycle. "IEEE transactions on biomedical engineering", 18 Novembre 2011, vol. 58, núm. 12, p. 3376-3385.
ISSN0018-9294
Publisher versionhttp://ieeexplore.ieee.org/xpls/abs_all.jsp?arnumber=5999711&tag=1
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