Calcium alternans produced by increased sarcoplasmic reticulum refractoriness
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Document typeConference report
Defense date2011
PublisherIEEE Computer Society Publications
Rights accessRestricted access - publisher's policy
Abstract
Despite the important role of electro-mechanical
alternans in cardiac arrhythmogenesis, its molecular
origin is not well understood. In this paper we want to
study alternans that can be associated with alternations
in the cytosolic calcium transient. To this end we study
particularly, how a malfunction of Ryanodine Receptor
(RyR) recovery time from inactivation may induce beatto-
beat alternations in intracellular calcium
concentration and how this could affect the stimulus
propagation in inhomogeneous tissue, whose cells exhibit
different calcium dynamics.
CitationCantalapiedra, I. R. [et al.]. Calcium alternans produced by increased sarcoplasmic reticulum refractoriness. A: Computing in Cardiology. "Proceedings: computing in cardiology". Hangzhou: IEEE Computer Society Publications, 2011, p. 645-648.
Publisher versionhttp://cataleg.upc.edu/record=b1383765~S1*cat
Collections
- Departament de Física Aplicada (fins octubre 2015) - Ponències/Comunicacions de congressos [242]
- GICITED - Grup Interdiciplinari de Ciència i Tecnologia en l'Edificació - Ponències/Comunicacions de congressos [104]
- NOLIN - Física No-Lineal i Sistemes Fora de l'Equilibri - Ponències/Comunicacions de congressos [49]
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