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dc.contributor.authorBenito, Antonio
dc.contributor.authorPérez, Guillermo M.
dc.contributor.authorMirabet, Sandra
dc.contributor.authorVilaseca Ricart, Meritxell
dc.contributor.authorPujol Ramo, Jaume
dc.contributor.authorMarín, José M.
dc.contributor.authorArtal, Pablo
dc.contributor.otherUniversitat Politècnica de Catalunya. Departament d'Òptica i Optometria
dc.date.accessioned2011-11-03T11:23:08Z
dc.date.available2011-11-03T11:23:08Z
dc.date.created2011-08-01
dc.date.issued2011-08-01
dc.identifier.citationBenito, A. [et al.]. Objective optical assessment of tear-film quality dynamics in normal and mildly symptomatic dry eyes. "Journal of cataract and refractive sugery", 01 Agost 2011, vol. 37, núm. 8, p. 1481-1487.
dc.identifier.issn0886-3350
dc.identifier.urihttp://hdl.handle.net/2117/13727
dc.description.abstractPURPOSE: To evaluate and compare the tear-film dynamics in normal eyes and in eyes with mild dry-eye symptoms using a new noninvasive optical method based on a double-pass instrument. SETTING: Hospital Universitario Virgen de la Arrixaca, Murcia, Spain. DESIGN: Evaluation of diagnostic test or technology. METHODS: Dynamic recording of double-pass retinal images during unforced tear-film breakup was performed in eyes with mild dry-eye symptoms (study group) and in an asymptomatic control group. Series of consecutive retinal images were recorded every 0.5 seconds while the patient avoided blinking. Measurements were performed under low-light conditions to naturally increase pupil diameter and maximize the method’s sensitivity. Additional clinical tests were performed for comparison and included tear breakup time (TBUT), Schirmer I tests, and a normalized questionnaire (McMonnies). From the retinal images, a quality metric, the intensity distribution index, was calculated. An objective TBUT value was estimated in each eye when the intensity distribution index surpassed a defined threshold value compared with the initial baseline. RESULTS: The study group comprised 20 eyes and the control group, 18 eyes. Symptomatic dry eyes had a typical exponential increase in the intensity distribution index with time. The objective TBUT values in the study group were comparable to the clinical TBUT estimates. CONCLUSIONS: The new objective optical method to evaluate the quality and stability of the tear film was sensitive in detecting mild symptoms of dry eye and differentiating from normal cases. The procedure may allow early detection and follow-up of patients’ tear film–related complaints.
dc.format.extent7 p.
dc.language.isoeng
dc.subjectÀrees temàtiques de la UPC::Ciències de la visió::Biologia ocular
dc.subject.lcshDry eye syndromes
dc.titleObjective optical assessment of tear-film quality dynamics in normal and mildly symptomatic dry eyes
dc.typeArticle
dc.subject.lemacUlls -- Malalties i defectes -- Diagnòstic i tractament
dc.contributor.groupUniversitat Politècnica de Catalunya. GREO - Grup de Recerca en Enginyeria Òptica
dc.identifier.doi10.1016/j.jcrs.2011.03.036
dc.description.peerreviewedPeer Reviewed
dc.rights.accessRestricted access - publisher's policy
local.identifier.drac5848302
dc.description.versionPostprint (published version)
local.citation.authorBenito, A.; Pérez, G.; Mirabet, S.; Vilaseca, M.; Pujol, J.; Marín, J.; Artal, P.
local.citation.publicationNameJournal of cataract and refractive sugery
local.citation.volume37
local.citation.number8
local.citation.startingPage1481
local.citation.endingPage1487


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