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dc.contributor.authorValle Mendoza, Luis Javier del
dc.contributor.otherUniversitat Politècnica de Catalunya. Departament d'Enginyeria Química
dc.coverage.spatialeast=-76.24006939999998; north=-9.929960600000001; name=Jirón General Prado 750, Huánuco 10001, Perú
dc.date.accessioned2019-03-27T16:54:29Z
dc.date.available2019-03-27T16:54:29Z
dc.date.issued2019-04-01
dc.identifier.citationdel Valle, LJ. Dengue diagnosis in an endemic area of Peru: Clinical characteristics and positive frequencies by RT-PCR and serology for NS1, IgM, and IgG. "International journal of infectious diseases", 1 Abril 2019, vol. 81, p. 31-37.
dc.identifier.issn1201-9712
dc.identifier.urihttp://hdl.handle.net/2117/130959
dc.description.abstractBackground: Huánuco is a central eastern region of Peru whose geography includes high forest and low jungle, as well as a mountain range that constitutes the inter-Andean valleys. It is considered a region endemic for dengue due to the many favorable conditions that facilitate transmission of the virus. Methods: A total of 268 serum samples from patients in Huánuco, Peru with an acute febrile illness were assessed for the presence of dengue virus (DENV) via RT-PCR and NS1, IgM, and IgG ELISA during December 2015 and March 2016. Results: DENV was detected in 25% of samples via RT-PCR, 19% of samples by NS1 antigen ELISA, and 10.5% of samples by IgM ELISA. DENV IgG was detected in 15.7% of samples by ELISA. The most frequent symptoms associated with fever across all groups were headache, myalgia, and arthralgia, with no significant difference between the four test methods Conclusions: In this study, DENV was identified in up to 25% of the samples using the standard laboratory method. In addition, a correlation was established between the frequency of positive results and the serological tests that determine NS1, IgM, and IgG. There is an increasing need for point-of-care tests to strengthen epidemiological surveillance in Peru.
dc.format.extent7 p.
dc.language.isoeng
dc.rightsAttribution-NonCommercial-NoDerivs 3.0 Spain
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/3.0/es/
dc.subjectÀrees temàtiques de la UPC::Enginyeria química
dc.subject.lcshDengue
dc.subject.lcshPeru
dc.subject.otherDengue
dc.subject.otherDENV
dc.subject.otherArbovirus
dc.subject.otherDiagnosis
dc.subject.otherPeru
dc.titleDengue diagnosis in an endemic area of Peru: Clinical characteristics and positive frequencies by RT-PCR and serology for NS1, IgM, and IgG
dc.typeArticle
dc.subject.lemacDengue
dc.subject.lemacPerú
dc.contributor.groupUniversitat Politècnica de Catalunya. PSEP - Polimers Sintètics: Estructura i Propietats. Polimers Biodegradables.
dc.identifier.doi10.1016/j.ijid.2019.01.022
dc.description.peerreviewedPeer Reviewed
dc.relation.publisherversionhttps://www.ijidonline.com/article/S1201-9712(19)30033-5/fulltext
dc.rights.accessOpen Access
drac.iddocument23944656
dc.description.versionPostprint (published version)
upcommons.citation.authordel Valle, LJ.
upcommons.citation.publishedtrue
upcommons.citation.publicationNameInternational journal of infectious diseases
upcommons.citation.volume81
upcommons.citation.startingPage31
upcommons.citation.endingPage37


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