This report summarises all the research activities performed by the APACHE project and highlights the main project outcomes and contributions. The APACHE Project proposes a new approach based on simulation, optimization and performance assessment tools, which aim to better capture ATM performance (by means of new or enhanced performance indicators), as well as the complex interdependencies between key performance areas (KPAs). Besides performing a thorough review on the SESAR 2020 Concept of Operations and different Performance Frameworks, the main contributions of the Project are the integration of several background tools into a single platform, enabling the “APACHE Framework”; the proposal and validation of 73 new (or enhanced) performance indicators; and the assessment of ATM interdependencies by using this Framework. This report briefly describes these contributions, highlighting the progress done beyond state-of-the-art methodologies in ATM performance assessment. This report also describes the links with the SESAR programme, identifying the potential uptake of results to Industrial Research and outlines potential future research and innovation activities.