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dc.contributor.authorHoyo Pérez, Javier
dc.contributor.authorIvanova, Kristina Dimitrova
dc.contributor.authorGuaus Guerrero, Ester
dc.contributor.authorTzanov, Tzanko
dc.contributor.otherUniversitat Politècnica de Catalunya. Departament d'Enginyeria Química
dc.identifier.citationHoyo, J. [et al.]. Multifunctional ZnO NPs-chitosan-gallic acid hybrid nanocoating to overcome contact lenses associated conditions and discomfort. "Journal of colloid and interface science", 1 May 2019, vol. 543, p.114-121
dc.description.abstractContact lenses (CL) provide visual correction but their use may also induce several adverse effects causative of discomfort and conditions that lead to stop or discontinue their use. Discomfort is mainly caused by insufficient wetting, impairment of the antioxidant defence system and eye infections. The current work reports on a single step sonochemical coating of CL with ZnO nanoparticles (NPs), chitosan (CS) and gallic acid (GA). GA and CS are expected to improve the comfort of CL by imparting respectively antioxidant properties and enhanced wettability, while their combination with ZnO NPs provides the CL with antimicrobial properties. The ternary composite coating presents high antibacterial efficiency (> 4.5 logs reduction) against S. aureus causative of CL-related conditions, and maintains good biocompatibility (> 72 %) with human cell lines. The obtained multi-functionality on the CL did not affect their geometry and refractive properties.
dc.rightsAttribution-NonCommercial-NoDerivs 3.0 Spain
dc.subjectÀrees temàtiques de la UPC::Enginyeria química
dc.subject.otherContact lenses
dc.subject.otherZnO nanoparticles
dc.subject.othergallic acid
dc.subject.otherantibacterial coating
dc.titleMultifunctional ZnO NPs-chitosan-gallic acid hybrid nanocoating to overcome contact lenses associated conditions and discomfort
dc.contributor.groupUniversitat Politècnica de Catalunya. GBMI - Grup de Biotecnologia Molecular i Industrial
dc.description.peerreviewedPeer Reviewed
dc.rights.accessRestricted access - publisher's policy
dc.description.versionPostprint (author's final draft)
local.citation.authorHoyo, J.; Ivanova, K.; Guaus, E.; Tzanov, T.
local.citation.publicationNameJournal of colloid and interface science

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Attribution-NonCommercial-NoDerivs 3.0 Spain
Except where otherwise noted, content on this work is licensed under a Creative Commons license : Attribution-NonCommercial-NoDerivs 3.0 Spain