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Multifunctional coatings and nanotopographies: toward cell instructive and antibacterial implants
dc.contributor.author | Mas Moruno, Carlos |
dc.contributor.author | Su, Bo |
dc.contributor.author | Dalby, Matthew J. |
dc.contributor.other | Universitat Politècnica de Catalunya. Departament de Ciència dels Materials i Enginyeria Metal·lúrgica |
dc.date.accessioned | 2018-12-21T13:50:00Z |
dc.date.available | 2019-11-22T01:26:11Z |
dc.date.issued | 2018-11-22 |
dc.identifier.citation | Mas-Moruno, C., Su, B., Dalby, M. Multifunctional coatings and nanotopographies: toward cell instructive and antibacterial implants. "Advanced healthcare materials", 22 Novembre 2018, vol. 7, núm. 23, p. 1-54. |
dc.identifier.issn | 2192-2640 |
dc.identifier.uri | http://hdl.handle.net/2117/126133 |
dc.description.abstract | In biomaterials science, it is nowadays well accepted that improving the biointegration of dental and orthopedic implants with surrounding tissues is a major goal. However, implant surfaces that support osteointegration may also favor colonization of bacterial cells. Infection of biomaterials and subsequent biofilm formation can have devastating effects and reduce patient quality of life, representing an emerging concern in healthcare. Conversely, efforts toward inhibiting bacterial colonization may impair biomaterial–tissue integration. Therefore, to improve the long-term success of medical implants, biomaterial surfaces should ideally discourage the attachment of bacteria without affecting eukaryotic cell functions. However, most current strategies seldom investigate a combined goal. This work reviews recent strategies of surface modification to simultaneously address implant biointegration while mitigating bacterial infections. To this end, two emerging solutions are considered, multifunctional chemical coatings and nanotopographical features. |
dc.format.extent | 54 p. |
dc.language.iso | eng |
dc.rights | Attribution-NonCommercial-NoDerivs 3.0 Spain |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/3.0/es/ |
dc.subject | Àrees temàtiques de la UPC::Enginyeria biomèdica::Biomecànica |
dc.subject.lcsh | Infection |
dc.subject.lcsh | Osseointegration |
dc.subject.lcsh | Biomedical materials |
dc.subject.lcsh | Biomechanics |
dc.subject.other | implant coatings |
dc.subject.other | infection |
dc.subject.other | multifunctional coatings |
dc.subject.other | nanotopographies |
dc.subject.other | osteointegration |
dc.title | Multifunctional coatings and nanotopographies: toward cell instructive and antibacterial implants |
dc.type | Article |
dc.subject.lemac | Infecció |
dc.subject.lemac | Biomecànica |
dc.subject.lemac | Materials biomèdics |
dc.contributor.group | Universitat Politècnica de Catalunya. BBT - Biomaterials, Biomecànica i Enginyeria de Teixits |
dc.identifier.doi | 10.1002/adhm.201801103 |
dc.description.peerreviewed | Peer Reviewed |
dc.rights.access | Open Access |
local.identifier.drac | 23555445 |
dc.description.version | Postprint (author's final draft) |
local.citation.author | Mas-Moruno, C.; Su, B.; Dalby, M. |
local.citation.publicationName | Advanced healthcare materials |
local.citation.volume | 7 |
local.citation.number | 23 |
local.citation.startingPage | 1 |
local.citation.endingPage | 54 |
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