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dc.contributor.authorHoyos Nogués, Mireia
dc.contributor.authorGil Mur, Francisco Javier
dc.contributor.authorMas Moruno, Carlos
dc.contributor.otherUniversitat Politècnica de Catalunya. Departament de Ciència dels Materials i Enginyeria Metal·lúrgica
dc.date.accessioned2018-10-17T08:23:21Z
dc.date.available2018-10-17T08:23:21Z
dc.date.issued2018-01-01
dc.identifier.citationHoyos, M., Gil, F.J., Mas-Moruno, C. Antimicrobial peptides: Powerful biorecognition elements to detect bacteria in biosensing technologies. "Molecules", 1 Gener 2018, vol. 23, núm. 7, p. 1683-1-1683-24.
dc.identifier.issn1420-3049
dc.identifier.urihttp://hdl.handle.net/2117/122434
dc.description.abstractBacterial infections represent a serious threat in modern medicine. In particular, biofilm treatment in clinical settings is challenging, as biofilms are very resistant to conventional antibiotic therapy and may spread infecting other tissues. To address this problem, biosensing technologies are emerging as a powerful solution to detect and identify bacterial pathogens at the very early stages of the infection, thus allowing rapid and effective treatments before biofilms are formed. Biosensors typically consist of two main parts, a biorecognition moiety that interacts with the target (i.e., bacteria) and a platform that transduces such interaction into a measurable signal. This review will focus on the development of impedimetric biosensors using antimicrobial peptides (AMPs) as biorecognition elements. AMPs belong to the innate immune system of living organisms and are very effective in interacting with bacterial membranes. They offer unique advantages compared to other classical bioreceptor molecules such as enzymes or antibodies. Moreover, impedance-based sensors allow the development of label-free, rapid, sensitive, specific and cost-effective sensing platforms. In summary, AMPs and impedimetric transducers combine excellent properties to produce robust biosensors for the early detection of bacterial infections
dc.language.isoeng
dc.rightsAttribution-NonCommercial-NoDerivs 3.0 Spain
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/3.0/es/
dc.subjectÀrees temàtiques de la UPC::Enginyeria química
dc.subject.lcshPeptides
dc.subject.lcshBiosensors
dc.subject.lcshBiofilms
dc.subject.lcshAntibiotics
dc.subject.otherAntimicrobial peptides
dc.subject.otherbacteria
dc.subject.otherbiofilm
dc.subject.otherbacterial detection
dc.subject.otherbiosensors
dc.subject.otherimpedance
dc.titleAntimicrobial peptides: Powerful biorecognition elements to detect bacteria in biosensing technologies
dc.typeArticle
dc.subject.lemacPèptids
dc.subject.lemacAntibiòtics
dc.subject.lemacBiosensors
dc.subject.lemacBiofilms
dc.contributor.groupUniversitat Politècnica de Catalunya. BBT - Biomaterials, Biomecànica i Enginyeria de Teixits
dc.identifier.doi10.3390/molecules23071683
dc.description.peerreviewedPeer Reviewed
dc.relation.publisherversionhttp://www.mdpi.com/1420-3049/23/7/1683
dc.rights.accessOpen Access
local.identifier.drac23311983
dc.description.versionPostprint (published version)
local.citation.authorHoyos, M.; Gil, F.J.; Mas-Moruno, C.
local.citation.publicationNameMolecules
local.citation.volume23
local.citation.number7
local.citation.startingPage1683-1
local.citation.endingPage1683-24


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Attribution-NonCommercial-NoDerivs 3.0 Spain
Except where otherwise noted, content on this work is licensed under a Creative Commons license : Attribution-NonCommercial-NoDerivs 3.0 Spain