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dc.contributor.authorGamarra Montes, Ana
dc.contributor.authorMissagia, Beatriz
dc.contributor.authorUrpí Garriga, Lourdes
dc.contributor.authorMorató Farreras, Jordi
dc.contributor.authorMuñoz Guerra, Sebastián
dc.contributor.otherUniversitat Politècnica de Catalunya. Departament d'Enginyeria Química
dc.contributor.otherUniversitat Politècnica de Catalunya. Departament d'Òptica i Optometria
dc.date.accessioned2018-10-11T09:39:03Z
dc.date.issued2018-10-01
dc.identifier.citationGamarra, A., Missagia, B., Urpí, L., Morato, J., Muñoz, S. Ionic coupling of hyaluronic acid with ethyl N-lauroyl L-arginate (LAE): Structure, properties and biocide activity of complexes. "Carbohydrate polymers", 1 Octubre 2018, vol. 197, núm. October 2018, p. 109-116.
dc.identifier.issn0144-8617
dc.identifier.urihttp://hdl.handle.net/2117/122201
dc.description.abstractEthyl alpha-N-lauroyl L-arginate hydrochloride (LAE) was coupled with hyaluronic acid (HyA) 2 to form ionic complexes with LAE to HyA ratios of 1:1 and 1:2. The complexes were extensively 3 characterized by FTIR and NMR spectroscopies and their thermal properties evaluated by 4 thermogravimetry and calorimetry. Thin films prepared from these complexes by casting 5 displayed a smectic-like structure based on an ordered arrangement of LAE and HyA layers 6 with a nanometric periodicity of 3.8-3.9 nm. Films immersed in water at pH 7.4 and 5.5 7 dissociated to deliver free LAE to the environment and reaching the equilibrium in few hours. 8 The biocide activity of these films against both Gram-positive and Gram-negative bacteria was 9 preliminary assessed by the liquid medium method, and shown to be notable in both cases. The 10 antibacterial property of the complexes was found to increase with the content of LAE and to be 11 particularly efficient against Gram-negative S. enterica bacteria.
dc.format.extent8 p.
dc.language.isoeng
dc.rightsAttribution-NonCommercial-NoDerivs 3.0 Spain
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/3.0/es/
dc.subjectÀrees temàtiques de la UPC::Enginyeria química
dc.subject.lcshAntimicrobial polymers
dc.subject.otherEthyl alpha-N-lauroyl L-arginate
dc.subject.otherLAE
dc.subject.otherhyaluronic acid
dc.subject.otherionic complexes
dc.subject.otherbiocide activity
dc.titleIonic coupling of hyaluronic acid with ethyl N-lauroyl L-arginate (LAE): Structure, properties and biocide activity of complexes
dc.typeArticle
dc.subject.lemacBiopolímers
dc.contributor.groupUniversitat Politècnica de Catalunya. POL - Polímers Industrials Avançats i Biopolímers Tecnològics
dc.contributor.groupUniversitat Politècnica de Catalunya. SUMMLab - Sustainability Measurement and Modeling Lab
dc.identifier.doi10.1016/j.carbpol.2018.05.057
dc.description.peerreviewedPeer Reviewed
dc.relation.publisherversionhttps://www.sciencedirect.com/science/article/pii/S014486171830599X
dc.rights.accessRestricted access - publisher's policy
drac.iddocument23243432
dc.description.versionPostprint (author's final draft)
dc.relation.projectidinfo:eu-repo/grantAgreement/MINECO/MAT2016-77345-C3-1-P
dc.date.lift2020-10-01
upcommons.citation.authorGamarra, A., Missagia, B., Urpí, L., Morato, J., Muñoz, S.
upcommons.citation.publishedtrue
upcommons.citation.publicationNameCarbohydrate polymers
upcommons.citation.volume197
upcommons.citation.numberOctober 2018
upcommons.citation.startingPage109
upcommons.citation.endingPage116


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Except where otherwise noted, content on this work is licensed under a Creative Commons license: Attribution-NonCommercial-NoDerivs 3.0 Spain