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Bioceramics and bone healing

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10.1302/2058-5241.3.170056
 
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hdl:2117/121936

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Ginebra Molins, Maria PauMés informacióMés informacióMés informació
Español Pons, MontserratMés informacióMés informacióMés informació
Maazouz, Yassine
Bergez, Victor
Pastorino Carraz, David
Document typeArticle
Defense date2018-05-01
Rights accessOpen Access
Attribution-NonCommercial-NoDerivs 3.0 Spain
Except where otherwise noted, content on this work is licensed under a Creative Commons license : Attribution-NonCommercial-NoDerivs 3.0 Spain
Abstract
- Calcium phosphates have long been used as synthetic bone grafts. Recent studies have shown that the modulation of composition and textural properties, such as nano-, micro- and macro-porosity, is a powerful strategy to control and synchronize material resorption and bone formation. - Biomimetic calcium phosphates, which closely mimic the composition and structure of bone mineral, can be produced using low-temperature processing routes, and offer the possibility to modulate the material properties to a larger extent than conventional high temperature sintering processes. - Advanced technologies open up new possibilities in the design of bioceramics for bone regeneration; 3D-printing technologies, in combination with the development of hybrid materials with enhanced mechanical properties, supported by finite element modelling tools, are expected to enable the design and fabrication of mechanically competent patient-specific bone grafts. - The association of ions, drugs and cells allows leveraging of the osteogenic potential of bioceramic scaffolds in compromised clinical situations, where the intrinsic bone regeneration potential is impaired.
CitationGinebra, M.P., Español, M., Maazouz, Y., Bergez, V., Pastorino, D. Bioceramics and bone healing. "EFORT Open Reviews", 1 Maig 2018, vol. 3, núm. May 2018, p. 173-183. 
URIhttp://hdl.handle.net/2117/121936
DOI10.1302/2058-5241.3.170056
ISSN2058-5241
Publisher versionhttps://online.boneandjoint.org.uk/doi/full/10.1302/2058-5241.3.170056
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  • Departament de Ciència dels Materials i Enginyeria Metal·lúrgica - Articles de revista [961]
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