Dielectric properties of colon polyps, cancer, and normal mucosa: Ex vivo measurements from 0.5 to 20 GHz
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Colorectal cancer is highly preventable by detecting and removing polyps, which are the precursors. 20 Currently, the most accurate test is colonoscopy, but still misses 22% of polyps due to visualization limitations. In this paper we preliminary assess the potential of microwave imaging and dielectric properties (e.g. complex permittivity) as a complementary method for detecting polyps and cancer tissue in the colon. The dielectric properties of biological tissues have been used in a wide variety of applications, including safety assessment of wireless technologies and design of medical diagnostic or therapeutic techniques 25 (microwave imaging, hyperthermia and ablation). The main purpose of this work is to measure the complex permittivity of different types of colon polyps, cancer and normal mucosa in ex vivo human samples to study if the dielectric properties are appropriate for classification purposes.
This is the accepted version of the following article: Guardiola, M. , Buitrago, S. , Fernández‐Esparrach, G. , O'Callaghan, J. M., Romeu, J. , Cuatrecasas, M. , Córdova, H. , González Ballester, M. Á. and Camara, O. (2018), Dielectric properties of colon polyps, cancer, and normal mucosa: Ex vivo measurements from 0.5 to 20 GHz. Med. Phys., 45: 3768-3782. doi:10.1002/mp.13016, which has been published in final form at https://aapm.onlinelibrary.wiley.com/doi/pdf/10.1002/mp.13016. This article may be used for non-commercial purposes in accordance with the Wiley Self-Archiving Policy [http://olabout.wiley.com/WileyCDA/Section/id-820227.html].
CitationGuardiola, M., Buitrago, S., Fernández-Esparrach, G., O'callaghan, J., Romeu, J., Cuatrecasas, M., Córdoba, H., González Ballester, Miguel A., Camara, O. Dielectric properties of colon polyps, cancer, and normal mucosa: Ex vivo measurements from 0.5 to 20 GHz. "Medical physics", 15 Juny 2018, vol. 45, núm. 8, p. 3768-3782.
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