Mostra el registre d'ítem simple
Comparison between gadolinium-enhanced 2D T1-weighted gradient-echo and spin-echo sequences in the detection of active multiple sclerosis lesions on 3.0T MRI
dc.contributor.author | Aymerich Martínez, Francisco Javier |
dc.contributor.author | Auger, Cristina |
dc.contributor.author | Alcaide, Paula |
dc.contributor.author | Pareto Onghena, Deborah |
dc.contributor.author | Huerga, Elena |
dc.contributor.author | Corral Gámez, Juan Francisco |
dc.contributor.author | Mitjana, Raquel |
dc.contributor.author | Sastre Garriga, Jaume |
dc.contributor.author | Montalban, Xavier |
dc.contributor.author | Rovira, Alex |
dc.contributor.other | Universitat Politècnica de Catalunya. Departament d'Enginyeria de Sistemes, Automàtica i Informàtica Industrial |
dc.date.accessioned | 2018-05-03T13:32:26Z |
dc.date.available | 2018-05-03T13:32:26Z |
dc.date.issued | 2017-04-01 |
dc.identifier.citation | Aymerich, F.X., Auger, C., Alcaide, P., Pareto, D., Huerga, E., Corral, J.F., Mitjana, R., Sastre, J., Montalban, X., Rovira, A. Comparison between gadolinium-enhanced 2D T1-weighted gradient-echo and spin-echo sequences in the detection of active multiple sclerosis lesions on 3.0T MRI. "European Radiology", 1 Abril 2017, vol. 27, núm. 4, p. 1361-1368. |
dc.identifier.issn | 0938-7994 |
dc.identifier.uri | http://hdl.handle.net/2117/116910 |
dc.description.abstract | Objectives To compare the sensitivity of enhancing multiple sclerosis (MS) lesions in gadolinium-enhanced 2D T1-weighted gradient-echo (GRE) and spin-echo (SE) sequences, and to assess the influence of visual conspicuity and laterality on detection of these lesions. Methods One hundred MS patients underwent 3.0T brain MRI including gadolinium-enhanced 2D T1-weighted GRE and SE sequences. The two sets of contrast-enhanced scans were evaluated in random fashion by three experienced readers. Lesion conspicuity was assessed by the image contrast ratio (CR) and contrast-to-noise ratio (CNR). The intracranial region was divided into four quadrants and the impact of lesion location on detection was assessed in each slice. Results Six hundred and seven gadolinium-enhancing MS lesions were identified. GRE images were more sensitive for lesion detection (0.828) than SE images (0.767). Lesions showed a higher CR in SE than in GRE images, whereas the CNR was higher in GRE than SE. Most misclassifications occurred in the right posterior quadrant. Conclusions The gadolinium-enhanced 2D T1-weighted GRE sequence at 3.0T MRI enables detection of enhancing MS lesions with higher sensitivity and better lesion conspicuity than 2D T1-weighted SE. Hence, we propose the use of gadolinium-enhanced GRE sequences rather than SE sequences for routine scanning of MS patients at 3.0T. Key Points • 2D SE and GRE sequences are useful for detecting active MS lesions. • Which of these sequences is more sensitive at high field remains uncertain. • GRE sequence showed better sensitivity for detecting active MS lesions than SE. • We propose GRE sequence for detecting active MS lesions at 3.0T. |
dc.format.extent | 8 p. |
dc.language.iso | eng |
dc.subject | Àrees temàtiques de la UPC::Ciències de la salut::Medicina::Diagnòstic per la imatge |
dc.subject.lcsh | Multiple sclerosis. |
dc.subject.lcsh | Diagnostic imaging |
dc.subject.other | Magnetic resonance imaging |
dc.subject.other | Brain |
dc.subject.other | Multiple sclerosis |
dc.subject.other | Contrast sensitivity |
dc.subject.other | Lesion conspicuity |
dc.title | Comparison between gadolinium-enhanced 2D T1-weighted gradient-echo and spin-echo sequences in the detection of active multiple sclerosis lesions on 3.0T MRI |
dc.type | Article |
dc.subject.lemac | Esclerosi múltiple |
dc.subject.lemac | Monitoratge de pacients |
dc.subject.lemac | Imatgeria per al diagnòstic |
dc.identifier.doi | 10.1007/s00330-016-4503-3 |
dc.relation.publisherversion | https://link.springer.com/article/10.1007%2Fs00330-016-4503-3 |
dc.rights.access | Open Access |
local.identifier.drac | 20329894 |
dc.description.version | Postprint (author's final draft) |
local.citation.author | Aymerich, F.X.; Auger, C.; Alcaide, P.; Pareto, D.; Huerga, E.; Corral, J.F.; Mitjana, R.; Sastre, J.; Montalban, X.; Rovira, A. |
local.citation.publicationName | European Radiology |
local.citation.volume | 27 |
local.citation.number | 4 |
local.citation.startingPage | 1361 |
local.citation.endingPage | 1368 |
Fitxers d'aquest items
Aquest ítem apareix a les col·leccions següents
-
Articles de revista [1.397]