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dc.contributor.authorBassegoda Puigdomenech, Arnau
dc.contributor.authorIvanova, Kristina Dimitrova
dc.contributor.authorRamon Portés, Eva
dc.contributor.authorTzanov, Tzanko
dc.contributor.otherUniversitat Politècnica de Catalunya. Departament d'Enginyeria Química
dc.date.accessioned2018-03-07T07:11:56Z
dc.date.available2019-03-01T01:30:21Z
dc.date.issued2018-02-01
dc.identifier.citationBassegoda, A., Ivanova, K., Ramon, E., Tzanov, T. Strategies to prevent the occurrence of resistance against antibiotics by using advanced materials. "Applied microbiology and biotechnology", 1 Febrer 2018, vol. 102, núm. 5, p. 2075-2089.
dc.identifier.issn0175-7598
dc.identifier.urihttp://hdl.handle.net/2117/114871
dc.descriptionThis is a post-peer-review, pre-copyedit version of an article published in Applied microbiology and biotechnology The final authenticated version is available online at: http://dx.doi.org/10.1007/s00253-018-8776-0
dc.description.abstractDrug resistance occurrence is a global healthcare concern responsible for the increased morbidity and mortality in hospitals, time of hospitalisation and huge financial loss. The failure of the most antibiotics to kill Bsuperbugs^ poses the urgent need to develop innovative strategies aimed at not only controlling bacterial infection but also the spread of resistance. The prevention of pathogen host invasion by inhibiting bacterial virulence and biofilm formation, and the utilisation of bactericidal agents with different mode of action than classic antibiotics are the two most promising new alternative strategies to overcome antibiotic resistance. Based on these novel approaches, researchers are developing different advanced materials (nanoparticles, hydrogels and surface coatings) with novel antimicrobial properties. In this review, we summarise the recent advances in terms of engineered materials to prevent bacteria-resistant infections according to the antimicrobial strategies underlying their design.
dc.format.extent15 p.
dc.language.isoeng
dc.rightsAttribution-NonCommercial-NoDerivs 3.0 Spain
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/3.0/es/
dc.subjectÀrees temàtiques de la UPC::Enginyeria química
dc.subject.lcshAntibiotics--Biotechnology
dc.subject.lcshTissue engineering
dc.subject.lcshNanoparticles--therapeutic use
dc.subject.otherAntibiotic resistance
dc.subject.otherantibiofouling
dc.subject.otherantimicrobial peptides
dc.subject.otherquorum sensing
dc.subject.othervirulence factors
dc.subject.othernano-antimicrobial materials
dc.titleStrategies to prevent the occurrence of resistance against antibiotics by using advanced materials
dc.typeArticle
dc.subject.lemacAntibiòtics -- Biotecnologia
dc.subject.lemacNanopartícules -- Ús terapèutic
dc.subject.lemacEnginyeria de teixits
dc.contributor.groupUniversitat Politècnica de Catalunya. GBMI - Grup de Biotecnologia Molecular i Industrial
dc.identifier.doi10.1007/s00253-018-8776-0
dc.description.peerreviewedPeer Reviewed
dc.rights.accessOpen Access
local.identifier.drac21885736
dc.description.versionPostprint (author's final draft)
local.citation.authorBassegoda, A.; Ivanova, K.; Ramon, E.; Tzanov, T.
local.citation.publicationNameApplied microbiology and biotechnology
local.citation.volume102
local.citation.number5
local.citation.startingPage2075
local.citation.endingPage2089


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Attribution-NonCommercial-NoDerivs 3.0 Spain
Except where otherwise noted, content on this work is licensed under a Creative Commons license : Attribution-NonCommercial-NoDerivs 3.0 Spain