Comparison of two discrimination indexes in the categorisation of continuous predictors in time-to-event studies
dc.contributor.author | Barrio, Irantzu |
dc.contributor.author | Rodríguez-Álvarez, María Xosé |
dc.contributor.author | Meira-Machado, Luis |
dc.contributor.author | Esteban, Cristóbal |
dc.contributor.author | Arostegui, Inmaculada |
dc.date.accessioned | 2018-01-12T15:44:36Z |
dc.date.available | 2018-01-12T15:44:36Z |
dc.date.issued | 2017-06-21 |
dc.identifier.citation | Barrio, I. [et al.]. Comparison of two discrimination indexes in the categorisation of continuous predictors in time-to-event studies. "SORT", 21 Juny 2017, vol. 1, p. 73-92. |
dc.identifier.issn | 1696-2281 |
dc.identifier.uri | http://hdl.handle.net/2117/112753 |
dc.description.abstract | The Cox proportionalhazards model is the most widely used su rvival prediction model for analysing time-to-event data. To measure the discrimination ability of a survival model the concordance probability index is widely used. In this work we studied and compared the performance of two different estimators of the concordance probability when a continuous predictor variable is cate- gorised in a Cox proportional hazards regression model. In p articular, we compared the c-index and the concordance probability estimator. We evaluated th e empirical performance of both es- timators through simulations. To categorise the predictor variable we propose a methodology which considers the maximal discrimination attained for th e categorical variable. We applied this methodology to a cohort of patients with chronic obstructiv e pulmonary disease, in particular, we categorised the predictor variable forced expiratory volu me in one second in percentage |
dc.format.extent | 20 p. |
dc.language.iso | eng |
dc.publisher | Institut d'Estadística de Catalunya |
dc.rights | Attribution-NonCommercial-NoDerivs 3.0 Spain |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/3.0/es/ |
dc.subject | Àrees temàtiques de la UPC::Matemàtiques i estadística::Estadística matemàtica |
dc.subject.other | Categorisation |
dc.subject.other | prediction models |
dc.subject.other | cutpoint |
dc.subject.other | Cox model |
dc.title | Comparison of two discrimination indexes in the categorisation of continuous predictors in time-to-event studies |
dc.type | Article |
dc.description.peerreviewed | Peer Reviewed |
dc.subject.ams | Classificació AMS::62 Statistics::62N Survival analysis and censored data |
dc.subject.ams | Classificació AMS::62 Statistics::62P Applications |
dc.rights.access | Open Access |
local.citation.publicationName | SORT |
local.citation.volume | 1 |
local.citation.startingPage | 73 |
local.citation.endingPage | 92 |
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