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dc.contributor.authorStanciuc, Ana Maria
dc.contributor.authorFlamant, Quentin
dc.contributor.authorSprecher, Christoph Martin
dc.contributor.authorAlini, Mauro
dc.contributor.authorAnglada Gomila, Marcos Juan
dc.contributor.authorPeroglio, Marianna
dc.contributor.otherUniversitat Politècnica de Catalunya. Departament de Ciència dels Materials i Enginyeria Metal·lúrgica
dc.date.accessioned2017-12-15T08:29:44Z
dc.date.issued2018-03
dc.identifier.citationStanciuc, A., Flamant, Q., Sprecher, C., Alini, M., Anglada, M., Peroglio, M. Femtosecond laser multi-patterning of zirconia for screening of cell-surface interactions. "Journal of the european ceramic society", Març 2018, vol. 38, núm. 3, p. 939-948.
dc.identifier.issn0955-2219
dc.identifier.urihttp://hdl.handle.net/2117/112116
dc.description.abstractYttria-stabilised tetragonal zirconia polycrystals (3Y-TZP) bioinert ceramics combine excellent strength and toughness, good aesthetics, high resistance to corrosion and absence of allergic reaction. However, improved osseointegration is needed as higher marginal bone loss was sometimes reported. In the present work, 3Y-TZP multi-patterned samples for rapid screening of cell-surface interactions were fabricated by femtosecond laser micromachining. Pits with well-defined edges and micrometric precision in pit diameter, depth and spacing were produced, as determined by white light interferometry. Pits showed a nanometric granular texture on the sidewalls and ripples at pit bottom, as attested by scanning electron microscopy. Focused ion beam analyses indicated limited laser-induced damage. Micropatterns impacted human mesenchymal stem cell (hMSC) size and morphology. Cell area and aspect ratio were mainly influenced by pit diameter, while solidity and circularity were affected by both pit diameter and depth. The pattern 30. µm diameter/10. µm depth induced the strongest osteoblastic hMSC commitment.
dc.format.extent10 p.
dc.language.isoeng
dc.publisherElsevier
dc.subjectÀrees temàtiques de la UPC::Enginyeria dels materials
dc.subject.lcshCell membranes
dc.subject.lcshZirconium
dc.subject.lcshCell culture
dc.subject.otherHuman Mesenchymal Stem Cells
dc.subject.otherLaser
dc.subject.otherPattern
dc.subject.otherSurface
dc.subject.otherTopography
dc.subject.otherZirconia
dc.titleFemtosecond laser multi-patterning of zirconia for screening of cell-surface interactions
dc.typeArticle
dc.subject.lemacMembranes cel·lulars
dc.subject.lemacZirconi
dc.contributor.groupUniversitat Politècnica de Catalunya. CIEFMA - Centre d'Integritat Estructural, Micromecànica i Fiabilitat dels Materials
dc.identifier.doi10.1016/j.jeurceramsoc.2017.08.019
dc.description.peerreviewedPeer Reviewed
dc.relation.publisherversionhttp://www.sciencedirect.com/science/article/pii/S0955221917305587?via%3Dihub
dc.rights.accessRestricted access - publisher's policy
local.identifier.drac21548309
dc.description.versionPostprint (published version)
dc.date.lift10000-01-01
local.citation.authorStanciuc, A.; Flamant, Q.; Sprecher, C.; Alini, M.; Anglada, M.; Peroglio, M.
local.citation.publicationNameJournal of the european ceramic society
local.citation.volume38
local.citation.number3
local.citation.startingPage939
local.citation.endingPage948


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