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Femtosecond laser multi-patterning of zirconia for screening of cell-surface interactions
dc.contributor.author | Stanciuc, Ana Maria |
dc.contributor.author | Flamant, Quentin |
dc.contributor.author | Sprecher, Christoph Martin |
dc.contributor.author | Alini, Mauro |
dc.contributor.author | Anglada Gomila, Marcos Juan |
dc.contributor.author | Peroglio, Marianna |
dc.contributor.other | Universitat Politècnica de Catalunya. Departament de Ciència dels Materials i Enginyeria Metal·lúrgica |
dc.date.accessioned | 2017-12-15T08:29:44Z |
dc.date.issued | 2018-03 |
dc.identifier.citation | Stanciuc, A., Flamant, Q., Sprecher, C., Alini, M., Anglada, M., Peroglio, M. Femtosecond laser multi-patterning of zirconia for screening of cell-surface interactions. "Journal of the european ceramic society", Març 2018, vol. 38, núm. 3, p. 939-948. |
dc.identifier.issn | 0955-2219 |
dc.identifier.uri | http://hdl.handle.net/2117/112116 |
dc.description.abstract | Yttria-stabilised tetragonal zirconia polycrystals (3Y-TZP) bioinert ceramics combine excellent strength and toughness, good aesthetics, high resistance to corrosion and absence of allergic reaction. However, improved osseointegration is needed as higher marginal bone loss was sometimes reported. In the present work, 3Y-TZP multi-patterned samples for rapid screening of cell-surface interactions were fabricated by femtosecond laser micromachining. Pits with well-defined edges and micrometric precision in pit diameter, depth and spacing were produced, as determined by white light interferometry. Pits showed a nanometric granular texture on the sidewalls and ripples at pit bottom, as attested by scanning electron microscopy. Focused ion beam analyses indicated limited laser-induced damage. Micropatterns impacted human mesenchymal stem cell (hMSC) size and morphology. Cell area and aspect ratio were mainly influenced by pit diameter, while solidity and circularity were affected by both pit diameter and depth. The pattern 30. µm diameter/10. µm depth induced the strongest osteoblastic hMSC commitment. |
dc.format.extent | 10 p. |
dc.language.iso | eng |
dc.publisher | Elsevier |
dc.subject | Àrees temàtiques de la UPC::Enginyeria dels materials |
dc.subject.lcsh | Cell membranes |
dc.subject.lcsh | Zirconium |
dc.subject.lcsh | Cell culture |
dc.subject.other | Human Mesenchymal Stem Cells |
dc.subject.other | Laser |
dc.subject.other | Pattern |
dc.subject.other | Surface |
dc.subject.other | Topography |
dc.subject.other | Zirconia |
dc.title | Femtosecond laser multi-patterning of zirconia for screening of cell-surface interactions |
dc.type | Article |
dc.subject.lemac | Membranes cel·lulars |
dc.subject.lemac | Zirconi |
dc.contributor.group | Universitat Politècnica de Catalunya. CIEFMA - Centre d'Integritat Estructural, Fiabilitat i Micromecànica dels Materials |
dc.identifier.doi | 10.1016/j.jeurceramsoc.2017.08.019 |
dc.description.peerreviewed | Peer Reviewed |
dc.relation.publisherversion | http://www.sciencedirect.com/science/article/pii/S0955221917305587?via%3Dihub |
dc.rights.access | Restricted access - publisher's policy |
local.identifier.drac | 21548309 |
dc.description.version | Postprint (published version) |
dc.date.lift | 10000-01-01 |
local.citation.author | Stanciuc, A.; Flamant, Q.; Sprecher, C.; Alini, M.; Anglada, M.; Peroglio, M. |
local.citation.publicationName | Journal of the european ceramic society |
local.citation.volume | 38 |
local.citation.number | 3 |
local.citation.startingPage | 939 |
local.citation.endingPage | 948 |
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