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dc.contributorLangohr, Klaus
dc.contributorTous, Sara
dc.contributorCleries, Ramon
dc.contributorAlemany, Laia
dc.contributor.authorFrias Gomez, Jon
dc.contributor.otherUniversitat Politècnica de Catalunya. Departament d'Estadística i Investigació Operativa
dc.description.abstractDuring the last 15 years, strong evidences have shown that some particular HPVs are involved etiologically in HNCs, especially in the oropharynx. However, this cancer etiology is multifactorial and tobacco and alcohol consumption also play an important role on it. In order to estimate the crude and adjusted HPV prevalence in HNCs, a study, which recruited HNC cases from 1990 to 2012 worldwide using different biological markers, as the presence of the virus DNA, E6*I mRNA, and p16INK4a expression, was conducted at ICO (Castellsagué X., et al., 2016). The aims of this MFP were: 1) To determine the variables associated to HPV infection in HNCs using unconditional logistic regression analysis with in international cross-sectional study. 2) To conduct a time series analysis using Bayesian methodology to evaluate how HPV prevalence in oropharyngeal cancers has evolved from 1990 until 2014 in Spain. 2.1) From a statistical point of view, we compared the results obtained with frequentist statistics to evaluate their benefits and inconveniences.
dc.publisherUniversitat Politècnica de Catalunya
dc.publisherUniversitat de Barcelona
dc.subjectÀrees temàtiques de la UPC::Matemàtiques i estadística::Estadística matemàtica
dc.subject.otherHuman Papillomavirus (HPV)
dc.subject.otherHead and Neck Cancer (HNC)
dc.subject.otherLogistic regression
dc.subject.otherLog binomial regression
dc.subject.otherPrevalence Odds Ratio (POR)
dc.subject.otherBayesian methodology
dc.subject.otherTime trend analyses.
dc.titleDeterminants of Human Papillomaviruses (HPVs) positivity in Head and Neck Cancers (HNCs) and Time trends of HPV positivity in Spanish oropharyngeal cancers, using Frequentist and Bayesian approaches
dc.typeMaster thesis
dc.subject.amsClassificació AMS::62 Statistics::62Q05 Statistical tables
dc.rights.accessRestricted access - author's decision
dc.audience.mediatorUniversitat Politècnica de Catalunya. Facultat de Matemàtiques i Estadística
dc.contributor.covenanteeInstitut Català d'Oncologia

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