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An anisotropic microsphere-based approach for fiber orientation adaptation in soft tissue
dc.contributor.author | Sáez Viñas, Pablo |
dc.contributor.author | Pena, Estefanía |
dc.contributor.author | Doblaré, Manuel |
dc.contributor.author | Martínez, Miguel Ángel |
dc.contributor.other | Universitat Politècnica de Catalunya. Departament d'Enginyeria Civil i Ambiental |
dc.date.accessioned | 2017-04-25T11:49:20Z |
dc.date.available | 2017-04-25T11:49:20Z |
dc.date.issued | 2011 |
dc.identifier.citation | Saez, P., Pena, E., Doblaré, M., Martínez, M.A. An anisotropic microsphere-based approach for fiber orientation adaptation in soft tissue. "IEEE transactions on biomedical engineering", 2011, vol. 58, núm. 12, p. 3500-3503. |
dc.identifier.issn | 0018-9294 |
dc.identifier.uri | http://hdl.handle.net/2117/103709 |
dc.description.abstract | Evolutionary processes in biological tissue, such as adaptation or remodeling, represent an enterprising area of research. In this paper, we present a multiscale model for the remodeling of fibered structures, such as bundles of collagen fibrils. With this aim, we introduce a von Mises statistical distribution function to account for the directional dispersion of the fibrils, and we remodel the underlying fibrils by changing their orientation. To numerically compute this process, we make use of the microsphere approach, which provides a useful multiscale tool for homogenizing the microstructure behavior, related to the fibrils of the bundle, in the macroscale of the problem. The results show how the fibrils respond to the stimulus by reorientation of their structure. This process leads to a stiffer material eventually reaching a stationary state. These results are in agreement with those reported in the literature, and they characterize the adaptation of biological tissue to external stimuli. |
dc.format.extent | 4 p. |
dc.language.iso | eng |
dc.subject | Àrees temàtiques de la UPC::Matemàtiques i estadística::Matemàtica aplicada a les ciències |
dc.subject | Àrees temàtiques de la UPC::Matemàtiques i estadística::Investigació operativa::Simulació |
dc.subject.lcsh | Strength of materials |
dc.subject.lcsh | Elasticity |
dc.title | An anisotropic microsphere-based approach for fiber orientation adaptation in soft tissue |
dc.type | Article |
dc.subject.lemac | Resistència de materials |
dc.subject.lemac | Elasticitat |
dc.contributor.group | Universitat Politècnica de Catalunya. LACÀN - Mètodes Numèrics en Ciències Aplicades i Enginyeria |
dc.identifier.doi | 10.1109/TBME.2011.2166154 |
dc.description.peerreviewed | Peer Reviewed |
dc.subject.ams | Classificació AMS::74 Mechanics of deformable solids::74P Optimization |
dc.subject.ams | Classificació AMS::74 Mechanics of deformable solids::74B Elastic materials |
dc.relation.publisherversion | http://ieeexplore.ieee.org/document/5999710/ |
dc.rights.access | Open Access |
local.identifier.drac | 19768930 |
dc.description.version | Postprint (author's final draft) |
local.citation.author | Saez, P.; Pena, E.; Doblaré, M.; Martínez, M.A. |
local.citation.publicationName | IEEE transactions on biomedical engineering |
local.citation.volume | 58 |
local.citation.number | 12 |
local.citation.startingPage | 3500 |
local.citation.endingPage | 3503 |
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