CCharPPI web server: computational characterization of protein–protein interactions from structure
10.1093/bioinformatics/btu594
Inclou dades d'ús des de 2022
Cita com:
hdl:2117/103452
Tipus de documentArticle
Data publicació2014-09-02
EditorOxford University Press
Condicions d'accésAccés obert
Tots els drets reservats. Aquesta obra està protegida pels drets de propietat intel·lectual i
industrial corresponents. Sense perjudici de les exempcions legals existents, queda prohibida la seva
reproducció, distribució, comunicació pública o transformació sense l'autorització del titular dels drets
ProjecteDESARROLLO DE NUEVAS METODOLOGIAS DE DOCKING ENTRE PROTEINAS PARA LOS RETOS DE INTERACTOMICA Y MEDICINA PERSONALIZADA (MINECO-BIO2013-48213-R)
EEPPIBM - Exploring the evolution of protein-protein interactions and their networks using biophysical models (EC-FP7-327899)
EEPPIBM - Exploring the evolution of protein-protein interactions and their networks using biophysical models (EC-FP7-327899)
Abstract
The atomic structures of protein–protein interactions are central to understanding their role in biological systems, and a wide variety of biophysical functions and potentials have been developed for their characterization and the construction of predictive models. These tools are scattered across a multitude of stand-alone programs, and are often available only as model parameters requiring reimplementation. This acts as a significant barrier to their widespread adoption. CCharPPI integrates many of these tools into a single web server. It calculates up to 108 parameters, including models of electrostatics, desolvation and hydrogen bonding, as well as interface packing and complementarity scores, empirical potentials at various resolutions, docking potentials and composite scoring functions.
CitacióMoal, I. H.; Jiménez-Garcia, B.; Fernández-Recio, J. CCharPPI web server: computational characterization of protein–protein interactions from structure. "Bioinformatics", 2 Setembre 2014, vol. 31, núm. 1, p. 123-125.
ISSN1367-4803
Col·leccions
Fitxers | Descripció | Mida | Format | Visualitza |
---|---|---|---|---|
CCharPPI web se ... al characterization of.pdf | 103,3Kb | Visualitza/Obre |