Ir al contenido (pulsa Retorno)

Universitat Politècnica de Catalunya

    • Català
    • Castellano
    • English
    • LoginRegisterLog in (no UPC users)
  • mailContact Us
  • world English 
    • Català
    • Castellano
    • English
  • userLogin   
      LoginRegisterLog in (no UPC users)

UPCommons. Global access to UPC knowledge

Banner header
69.085 UPC E-Prints
You are here:
View Item 
  •   DSpace Home
  • E-prints
  • Departaments
  • Departament de Ciència dels Materials i Enginyeria Metal·lúrgica
  • Articles de revista
  • View Item
  •   DSpace Home
  • E-prints
  • Departaments
  • Departament de Ciència dels Materials i Enginyeria Metal·lúrgica
  • Articles de revista
  • View Item
JavaScript is disabled for your browser. Some features of this site may not work without it.

avß3- or a5ß1-Integrin-Selective Peptidomimetics for Surface Coating

Thumbnail
View/Open
Mas-Moruno et al_Angewandte2016.pdf (1,597Mb)
 
10.1002/anie.201509782
 
  View UPCommons Usage Statistics
  LA Referencia / Recolecta stats
Includes usage data since 2022
Cita com:
hdl:2117/102501

Show full item record
Mas Moruno, CarlosMés informacióMés informacióMés informació
Fraioli, Roberta
Rechenmacher, Florian
Neubauer, Stefanie
Kapp, Tobias G.
Kessler, Horst
CovenanteeTechnische Universität München
Document typeArticle
Defense date2016-06-13
Rights accessOpen Access
Attribution-NonCommercial-NoDerivs 3.0 Spain
This work is protected by the corresponding intellectual and industrial property rights. Except where otherwise noted, its contents are licensed under a Creative Commons license : Attribution-NonCommercial-NoDerivs 3.0 Spain
Abstract
Engineering biomaterials with integrin-binding activity is a very powerful approach to promote cell adhesion, modulate cell behavior, and induce specific biological responses at the surface level. The aim of this Review is to illustrate the evolution of surface-coating molecules in this field: from peptides and proteins with relatively low integrin-binding activity and receptor selectivity to highly active and selective peptidomimetic ligands. In particular, we will bring into focus the difficult challenge of achieving selectivity between the two closely related integrin subtypes avß3 and a5ß1. The functionalization of surfaces with such peptidomimetics opens the way for a new generation of highly specific cell-instructive surfaces to dissect the biological role of integrin subtypes and for application in tissue engineering and regenerative medicine.
CitationMas-Moruno, C., Fraioli, R., Rechenmacher, F., Neubauer, S., Kapp, T., Kessler, H. avß3- or a5ß1-Integrin-Selective Peptidomimetics for Surface Coating. "Angewandte chemie. International edition", 13 Juny 2016, vol. 55, núm. 25, p. 7048-7067. 
URIhttp://hdl.handle.net/2117/102501
DOI10.1002/anie.201509782
ISSN1433-7851
Publisher versionhttp://onlinelibrary.wiley.com/doi/10.1002/anie.201509782/abstract
Collections
  • Departament de Ciència dels Materials i Enginyeria Metal·lúrgica - Articles de revista [960]
  • BBT - Grup de recerca en Biomaterials, Biomecànica i Enginyeria de Teixits - Articles de revista [479]
  View UPCommons Usage Statistics

Show full item record

FilesDescriptionSizeFormatView
Mas-Moruno et al_Angewandte2016.pdf1,597MbPDFView/Open

Browse

This CollectionBy Issue DateAuthorsOther contributionsTitlesSubjectsThis repositoryCommunities & CollectionsBy Issue DateAuthorsOther contributionsTitlesSubjects

© UPC Obrir en finestra nova . Servei de Biblioteques, Publicacions i Arxius

info.biblioteques@upc.edu

  • About This Repository
  • Metadata under:Metadata under CC0
  • Contact Us
  • Send Feedback
  • Privacy Settings
  • Inici de la pàgina