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dc.contributor.authorBendezú García, Álvaro
dc.contributor.authorBarba, Elisabeth
dc.contributor.authorBurri, Emanuel
dc.contributor.authorCisternas, Daniel
dc.contributor.authorAccarino Garaventa, Anna María
dc.contributor.authorQuiroga, Sergi
dc.contributor.authorMonclús Lahoya, Eva
dc.contributor.authorNavazo Álvaro, Isabel
dc.contributor.authorMalagelada Benapres, Juan Ramon
dc.contributor.authorAzpiroz Vidaur, Fernando
dc.contributor.otherUniversitat Politècnica de Catalunya. Departament de Ciències de la Computació
dc.identifier.citationBendezú, Á., Barba, E., Burri, E., Cisternas, D., Accarino, A., Quiroga, S., Monclús, E., Navazo, I., Malagelada, J., Azpiroz, F. Colonic content in health and its relation to functional gut symptoms. "Neurogastroenterology and motility", 12 Febrer 2016, vol. 28, núm. 6, p. 849-854.
dc.descriptionThis is the peer reviewed version of the following article: Bendezú, R. A., Barba, E., Burri, E., Cisternas, D., Accarino, A., Quiroga, S., Monclus, E., Navazo, I., Malagelada, J.-R. and Azpiroz, F. (2016), Colonic content in health and its relation to functional gut symptoms. Neurogastroenterol. Motil., 28: 849–854, which has been published in final form at [doi:10.1111/nmo.12782]. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Self-Archiving
dc.description.abstractGut content may be determinant in the generation of digestive symptoms, particularly in patients with impaired gut function and hypersensitivity. Since the relation of intraluminal gas to symptoms is only partial, we hypothesized that non-gaseous component may play a decisive role. Methods: Abdominal computed tomography scans were evaluated in healthy subjects during fasting and after a meal (n = 15) and in patients with functional gut disorders during basal conditions (when they were feeling well) and during an episode of abdominal distension (n = 15). Colonic content and distribution were measured by an original analysis program. Key results: In healthy subjects both gaseous (87 ± 24 mL) and non-gaseous colonic content (714 ± 34 mL) were uniformly distributed along the colon. In the early postprandial period gas volume increased (by 46 ± 23 mL), but non-gaseous content did not, although a partial caudad displacement from the descending to the pelvic colon was observed. No differences in colonic content were detected between patients and healthy subjects. Symptoms were associated with discrete increments in gas volume. However, no consistent differences in non-gaseous content were detected in patients between asymptomatic periods and during episodes of abdominal distension. Conclusions & inferences: In patients with functional gut disorders, abdominal distension is not related to changes in non-gaseous colonic content. Hence, other factors, such as intestinal hypersensitivity and poor tolerance of small increases in luminal gas may be involved.
dc.format.extent6 p.
dc.subjectÀrees temàtiques de la UPC::Informàtica::Aplicacions de la informàtica
dc.subjectÀrees temàtiques de la UPC::Ciències de la salut::Medicina::Diagnòstic per la imatge
dc.subject.lcshGastrointestinal gas
dc.titleColonic content in health and its relation to functional gut symptoms
dc.subject.lemacGasos gastrointestinals
dc.contributor.groupUniversitat Politècnica de Catalunya. ViRVIG - Grup de Recerca en Visualització, Realitat Virtual i Interacció Gràfica
dc.description.peerreviewedPeer Reviewed
dc.rights.accessOpen Access
dc.description.versionPostprint (author's final draft)
upcommons.citation.authorBendezú, Á.; Barba, E.; Burri, E.; Cisternas, D.; Accarino, A.; Quiroga, S.; Monclús, E.; Navazo, I.; Malagelada, J.; Azpiroz, F.
upcommons.citation.publicationNameNeurogastroenterology and motility

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