Assessing motor fluctuations in Parkinson’s disease patients based on a single inertial sensor
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Data publicació2016-12-15
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Abstract
Altered movement control is typically the first noticeable symptom manifested by
Parkinson’s disease (PD) patients. Once under treatment, the effect of the medication is very patent
and patients often recover correct movement control over several hours. Nonetheless, as the disease
advances, patients present motor complications. Obtaining precise information on the long-term
evolution of these motor complications and their short-term fluctuations is crucial to provide
optimal therapy to PD patients and to properly measure the outcome of clinical trials. This paper
presents an algorithm based on the accelerometer signals provided by a waist sensor that has been
validated in the automatic assessment of patient’s motor fluctuations (ON and OFF motor states)
during their activities of daily living. A total of 15 patients have participated in the experiments in
ambulatory conditions during 1 to 3 days. The state recognised by the algorithm and the motor state
annotated by patients in standard diaries are contrasted. Results show that the average specificity
and sensitivity are higher than 90%, while their values are higher than 80% of all patients, thereby
showing that PD motor status is able to be monitored through a single sensor during daily life of
patients in a precise and objective way.
CitacióPerez, C., Sama, A., Rodriguez-Martin, D., Catala, A., Cabestany, J., Moreno, J., De Mingo, E., Rodríguez, A. Assessing motor fluctuations in Parkinson’s disease patients based on a single inertial sensor. "Sensors", 15 Desembre 2016, vol. 16, núm. 12, p. 1-25.
ISSN1424-8220
Versió de l'editorhttp://www.mdpi.com/1424-8220/16/12/2132
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