Evaluation of bone loss in antibacterial coated dental implants: an experimental study in dogs
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hdl:2117/101441
Realitzat a/ambUniversitat de Barcelona. Departament de Patologia i Terapèutica Experimental; University of Calgary. McCaig Institute for Bone and Joint Health
Tipus de documentArticle
Data publicació2016-07
EditorElsevier
Condicions d'accésAccés obert
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Reconeixement-NoComercial-SenseObraDerivada 3.0 Espanya
Abstract
The aim of this study was to evaluate the in vivo effect of antibacterial modified dental implants in the first stages of peri-implantitis. Thirty dental implants were inserted in the mandibular premolar sites of 5 beagle dogs. Sites were randomly assigned to Ti (untreated implants, 10 units), Ti_Ag (silver electrodeposition treatment, 10 units), and Ti_TSP (silanization treatment, 10 units). Coated implants were characterized by scanning electron microscopy, interferometry and X-ray photoelectron spectroscopy. Two months after implant insertion, experimental peri-implantitis was initiated by ligature placement. Ligatures were removed 2 months later, and plaque formation was allowed for 2 additional months. Clinical and radiographic analyses were p¬erformed during the study. Implant-tissue samples were prepared for micro computed tomography, backscattered scanning electron microscopy, histomorphometric and histological analyses and ion release measurements. X-ray, SEM and histology images showed that vertical bone resorption in treated implants was lower than in the control group (P < 0.05). This effect is likely due to the capacity of the treatments to reduce bacteria colonization on the implant surface. Histological analysis suggested an increase of peri-implant bone formation on silanized implants. However, the short post-ligature period was not enough to detect differences in clinical parameters among implant groups. Within the limits of this study, antibacterial surface treatments have a positive effect against bone resorption induced by peri-implantitis.
CitacióGodoy-Gallardo, M., Manzanares, M., Sevilla, P., Nart, J., Manzanares, N., Manero, J., Gil, J., Boyd, S.K., Rodriguez, D. Evaluation of bone loss in antibacterial coated dental implants: an experimental study in dogs. "Materials science and engineering C. Biomimetic and supramolecular systems", Juliol 2016, vol. 69, p. 538-545.
ISSN0928-4931
Versió de l'editorhttp://www.sciencedirect.com/science/article/pii/S0928493116306944
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