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13.240 Articles in journals published by the UPC
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On equivalence and bioequivalence testing

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Ocaña Rebull, JordiMés informació
Sánchez Olavarría, María Pilar
Sánchez, Alex
Carrasco Jordan, Josep Lluís
Document typeArticle
Defense date2008
PublisherInstitut d'Estadística de Catalunya
Rights accessOpen Access
Attribution-NonCommercial-NoDerivs 3.0 Spain
Except where otherwise noted, content on this work is licensed under a Creative Commons license : Attribution-NonCommercial-NoDerivs 3.0 Spain
Abstract
Equivalence testing is the natural approach to many statistical problems. First, its main application, bioequivalence testing, is reviewed. The basic concepts of bioequivalence testing (2×2 crossover designs, TOST, interval inclusion principle, etc.) and its problems (TOST biased character, the carryover problem, etc.) are considered. Next, equivalence testing is discussed more generally. Some applications and methods are reviewed and the relation of equivalence testing and distance-based inference is highlighted. A new distance-based method to determine whether two gene lists are equivalent in terms of their annotations in the Gene Ontology illustrates these ideas. We end with a general discussion and some suggestions for future research.
CitationOcaña i Rebull, Jordi [et al.]. On equivalence and bioequivalence testing. "SORT", 2008, vol. 32, núm. 2, p. 151-176. 
URIhttp://hdl.handle.net/2099/8935
ISSN1696-2281
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  • SORT (Statistics and Operations Research Transactions) - 2008, Vol. 32, Núm. 2 [4]
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