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dc.contributor.authorFlores, Carlos
dc.contributor.authorRodríguez-Girondo, Mar
dc.contributor.authorCadarso-Suárez, Carmen
dc.contributor.authorKneib, Thomas
dc.contributor.authorGómez Melis, Guadalupe
dc.contributor.authorCasanova, Luís
dc.date.accessioned2013-05-21T15:13:36Z
dc.date.available2013-05-21T15:13:36Z
dc.date.issued2012
dc.identifier.citationFlores, Carlos [et al.]. Flexible geoadditive survival analysis of non-Hodgkin lymphoma in Peru. "SORT", vol. 36, núm. 2, p. 221-230.
dc.identifier.issn1696-2281
dc.identifier.urihttp://hdl.handle.net/2099/13325
dc.description.abstractKnowledge of prognostic factors is an important task for the clinical management of Non Hodgkin Lymphoma (NHL). In this work, we study the variables affecting survival of NHL in Peru by means of geoadditive Cox-type structured hazard regression models while accounting for potential spatial correlations in the survival times. We identified eight covariates with significant effect for overall survival. Some of them are widely known such as age, performance status, clinical stage and lactic dehydrogenase, but we also identified hemoglobin, leukocytes and lymphocytes as covariates with a significant effect on the overall survival of patients with NHL. Besides, the effect of continuous covariates is clearly nonlinear and hence impossible to detect with the classical Cox method. Although the spatial component does not show a significant effect, the results show a trend of low risk in certain areas
dc.format.extent10 p.
dc.language.isoeng
dc.publisherInstitut d'Estadística de Catalunya
dc.relation.ispartofSORT. 2012, vol. 36, núm. 2
dc.rightsAttribution-NonCommercial-NoDerivs 3.0 Spain
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/3.0/es/
dc.subjectÀrees temàtiques de la UPC::Matemàtiques i estadística::Estadística matemàtica
dc.subject.lcshMathematical statistics
dc.subject.otherNon-Hodgkin lymphoma
dc.subject.otherstructured regression models
dc.subject.othersurvival analysis
dc.titleFlexible geoadditive survival analysis of non-Hodgkin lymphoma in Peru
dc.typeArticle
dc.subject.lemacEstadística matemàtica--Aplicacions
dc.description.peerreviewedPeer Reviewed
dc.subject.amsClassificació AMS::62 Statistics::62P Applications
dc.subject.amsClassificació AMS::62 Statistics::62N Survival analysis and censored data
dc.rights.accessOpen Access
local.citation.authorFlores, Carlos; Rodríguez-Girondo, Mar; Cadarso-Suárez, Carmen; Kneib, Thomas; Gómez Melis, Guadalupe; Casanova, Luís
local.citation.publicationNameSORT
local.citation.volume36
local.citation.number2
local.citation.startingPage221
local.citation.endingPage230


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