Cuantificación de la dosis en superficie en radioterapia: Simulación Monte Carlo y medidas con cámara de extrapolación
Tutor / directorDuch Guillen, María Amor
Document typeMaster thesis
Rights accessOpen Access
All rights reserved. This work is protected by the corresponding intellectual and industrial property rights. Without prejudice to any existing legal exemptions, reproduction, distribution, public communication or transformation of this work are prohibited without permission of the copyright holder
During a radiotherapy treatment, skin of the patient is always exposed to the radiation; as a consequence late effects can be appear. Therefore, dose values in this region may be of interest for clinical evaluation and investigation of those undesirable effects. However, surface dose is not intuitive and is difficult to measure and calculate; the parameters, which modify it are not always the same and each one are dependent to the others. The aim of this project is to quantify absorbed dose in the build-up region and near to the skin approximately between 0 mm - 1 mm using two methods. One of them, an analytical calculation using Monte Carlo simulations; and the other an experimental approach using an extrapolation chamber. Monte Carlo simulations are performed with the PENELOPE package of subroutines for 6MV and 15MV photon beams. Experimental setup consists in the use of an extrapolation chamber (PTW model 23392), considered the most suitable instrument to measure absorbed dose in the build-up region, but its not commonly available in the hospitals because its use is not practical. The chamber was adapted for its use in clinical environments in a previous work, then for this work the measurement process is easier and results with high level of accuracy can be obtained. In this way, EC (extrapolation chamber) measurements served as the gold standard in our study to validate the Monte Carlo simulations and also with results reported by previous studies. As a result, we found that simulation outcomes are in good agreement with experimental data.
SubjectsRadiation -- Dosimetry, Radiation -- Dosage -- Simulation methods, Radiotherapy, Monte Carlo method, Radiació -- Dosimetria, Radiació -- Dosificació -- Mètodes de simulació, Radioteràpia, Montecarlo, Mètode de
DegreeMÀSTER UNIVERSITARI EN ENGINYERIA BIOMÈDICA (Pla 2009)