Microwave monitoring of biodegradable stents
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Abstract
The main goal of this work is to use Microwave Spectrometry (MWS) techniques to monitor the degradation/ageing process of biodegradable stents. To do so, we will first measure three metallic biodegradable stents of different lengths and the same diameter sunken in Ringer Lactate Solution (RLS); given that this solution emulates blood's physiological properties, the stents will gradually degrade. During this process, we will analyse how our spectral response changes along time. Secondly, to slow down the degradation process and match the time it would take $in-vivo$, stents will be wrapped in coronary arteries and measured in RLS. Lastly, stents will undergo a series of cuts in order to compare their spectral behaviour when fractured to that of non-degradable stents. Results will show how the stent degradation process can be monitored by means of MWS; additionally, this work will also show how response of both non-biodegradable and biodegradable stents is comparable, thus allowing to monitor not only the degradation process of the latter but their faults too.
Descripció
The advent of biodegradable stents as a solution to human arteries obstructions may overcome pathologies related to former non-degradable stents. In this work we aim to characterize these state-of-the-art prosthetic devices using near-field probes to couple with magnesium biodegradable stents. By analysing the transmission coefficient (S21) we intend to monitor the degradation process over time under in vivo-like conditions, as well as to detect structural defects in the stent?s scaffold.

