Mine planning and mine design are crucial stages of a project in the mining industry. This study aimed to determine the impact of different constraints on the design and planning of a mine. Some of the deposit characteristics and parameters that influence the economic feasibility of a project were studied. Using economic criteria such as NPV, scenarios were established based on the best conditions to obtain higher profitability. Production was identified as the most relevant variable. Subsequently, the mining design was evaluated through technical parameters such as slope gradients and ramp widths, and it was identified that they have lower sensitivity in the final design and higher sensitivity in terms of economic feasibility, performance, and environmental implications. Using operational production, the performance of the loading and haulage equipment fleets was evaluated for each of the techno-economic scenarios. Additionally, the environmental cost was compared using equipment fuel consumption and CO2 emissions. This study presents a practical methodology for analyzing relevant variables in mining projects, their interactions, and identifying potential scenarios.