Microwave and microfluidic techniques may enable wireless monitoring and interaction with bio-particles, yet still is a largely uncharted territory. Fortunately, the requirements of microfluidics and microwave techniques converge to the need of system miniaturization for reaching the sensitivity levels required. Accordingly, in this work, it is presented the design and optimization of a measurement setup for the system-level characterization of different designs of bio-particle-sensing coplanar-electrodes on a microfluidic-platform.

The design of the signal-chain of the measurement setup is optimized for a RF Phase-Sensitive Homodyne Receiver. In addition, the signal-integrity is achieved with a microwave-shielded-chamber, protecting from electromagnetic interference the coplanar electrodes on a microfluidic platform. As well, experimental validation of the system-level performance of the measurement setup are provided, for different coplanar-electrodes designs.