This chapter presents the results of a testing and validation activity carried out to analyze the performance of signal-processing techniques related to positioning and navigation. The steps included the setup of a measurement campaign and the setup of a shared database, the usage of this database to test algorithms, and the development of a software defined radio (SDR)-based architecture for a GNSS receiver, to be used for advanced laboratory tests on innovative GNSS-related signal processing algorithms. During the measurement campaign, a total of 22 ZigBee-based devices, model CC2430 made by Texas Instruments, were used to measure RSS values. Each of them is a single chip solution which integrates microprocessor and radio interface compliant with the IEEE 802.15.4 standard at 2.4 GHz. Two UWB-based devices, model PulsOn220 made by Time Domain, were used to perform TOA ranging measurements in both static and dynamic scenarios. During the test, the receiver in light-indoor condition could autonomously track only one satellite, identified as PRN 9. This PRN was also tracked by the aiding user; therefore, it was used to estimate the clock offset among the two PCs.