This deliverable presents a report on the developed actions and results concerning Digital-Twin-enabled multi-physics simulations and model matching. Enabling meaningful simulations within new human-infrastructure interfaces such as Digital twins is paramount. Accessing the power of simulation opens manifold new ways for observation, understanding, analysis and prediction of numerous scenarios to which the asset may be faced. As a result, managers can access countless ways of acquiring synthetic data for eventually taking better, more informed decisions. The tool MatchFEM is conceived as a fundamental part of this endeavour. From a broad perspective, the tool is aimed at contextualizing information between multi-physics simulations and vaster information constructs such as digital twins. 3D geometries, measurements, simulations, and asset management coexist in such information constructs. This report provides guidance for the generation of comprehensive adequate initial conditions of the assets to be used during their life span using a DT basis. From a more specific focus, this deliverable presents a set of exemplary recommendations for the development of DT-enabled load tests of assets in the form of a white paper. The deliverable also belongs to a vaster suit of documents encountered in WP5 of the Ashvin project in which measurements, models and assessments are described thoroughly.