Nowadays, hydropower is demanded to provide flexibility and fast response into the electrical grid in order to compensate the non-constant electricity generation of other renewable sources. Hydraulic turbines are therefore demanded to work under o -design conditions more frequently, where di erent complex hydraulic phenomena appear, a ecting the machine stability as well as reducing the useful life of its components. Hence, it is desirable to detect in real-time these hydraulic phenomena to assess the operation of the machine. In this paper, a large medium-head Francis turbine was selected for this purpose. This prototype is instrumented with several sensors such as accelerometers, proximity probes, strain gauges, pressure sensors and a microphone. Results presented in this paper permit knowing which hydraulic phenomenon is detected with every sensor and which signal analysis technique is necessary to use. With this information, monitoring systems can be optimized with the most convenient sensors, locations and signal analysis techniques