Now showing items 1-5 of 5

  • 5-HTTLPR polymorphism, mood disorders and MDMA use in a 3-year follow-up study 

    de la Torre, Rafael; Martín-Santos, Rocío; Torrens, M.; Poudevida, Sandra; Langohr, Klaus; Cuyas, Elisabet; Pacifici, Roberta; Farré, Magí; Pichini, Simona (2010-01)
    Article
    Restricted access - publisher's policy
    A 3-year longitudinal prospective study was conducted to compare the incidence of substance use disorders (SUD) and non-substance use disorders (NSUD) among ecstasy users and two control groups: one of cannabis users and ...
  • A lower olfactory capacity Is related to higher circulating concentrations of endocannabinoid 2-arachidonoylglycerol and higher body mass index in women 

    Pastor, Antoni; Fernández-Aranda, Fernando; Fitó, Montserrat; Jiménez-Murcia, Susana; Botella, Cristina; Fernández-Real, Jose M.; Frühbeck, Gema; Tinahones, Francisco; Fagundo, Ana; Rodriguez, Joan; Agüera, Zaida; Langohr, Klaus; Casanueva, Felipe F.; de la Torre, Rafael (2016)
    Article
    Open Access
    The endocannabinoid (eCB) system can promote food intake by increasing odor detection in mice. The eCB system is over-active in human obesity. Our aim is to measure circulating eCB concentrations and olfactory capacity in ...
  • Clinical Pharmacology of 3,4-Methylenedioxymethamphetamine (MDMA, "Ecstasy''): the influence of gender and genetics (CYP2D6, COMT, 5-HTT) 

    Pardo-Lozano, Ricardo; Farré, Magí; Yubero-Lahoz, Samanta; O’Mathúna, Brian; Torrens, M.; Mustata, Cristina; Pérez-Mañá, Clara; Langohr, Klaus; Cuyàs, Elisabet; Carbó, Marcel·lí; de la Torre, Rafael (2012-10-24)
    Article
    Open Access
    The synthetic psychostimulant MDMA (63,4-methylenedioxymethamphetamine, ecstasy) acts as an indirect serotonin, dopamine, and norepinephrine agonist and as a mechanism-based inhibitor of the cytochrome P-450 2D6 (CYP2D6). ...
  • The influence of 5-HTT and COMT genotypes on verbal fluency in ecstasy users 

    Fagundo, Ana B.; Cuyas, Elisabet; Verdejo Garcia, Antonio; Khymenets, Olha; Langohr, Klaus; Martín-Santos, Rocío; Farré, Magí; de la Torre, Rafael (2010-09)
    Article
    Restricted access - publisher's policy
    Deficits in verbal fluency associated with ecstasy use have been well established; however, the mechanisms underlying this impairment have yet to be elucidated. In this study we investigated for the first time whether there ...
  • VNTR-DAT1 and COMTVal158Met genotypes modulate mental flexibility and adaptive behavior skills in Down syndrome 

    del Hoyo, Laura; Xicota, Laura; Langohr, Klaus; Sánchez Benavides, Gonzalo; de Sola Llopis, Susana; Cuenca Royo, Aida; Rodríguez, Joan; Farré, Magí; Dierssen, Mara; de la Torre, Rafael (2016-10-17)
    Article
    Open Access
    Down syndrome (DS) is an aneuploidy syndrome that is caused by trisomy for human chromosome 21 resulting in a characteristic cognitive and behavioral phenotype, which includes executive functioning and adaptive behavior ...