Browsing by Author "Wagener, Rabea"

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Mutational mechanisms shaping the coding and noncoding genome of germinal center derived B-cell lymphomas

Hübschmann, Daniel; Kleinheinz, Kortine; Wagener, Rabea; Bernhart, Stephan H.; Valencia, Alfonso (Springer Nature, 2021)
Article
Open Access
B cells have the unique property to somatically alter their immunoglobulin (IG) genes by V(D)J recombination, somatic hypermutation (SHM) and class-switch recombination (CSR). Aberrant targeting of these mechanisms is ...