Browsing by Author "Vilaplana, Cristina"
Now showing items 1-10 of 10
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Can systems immunology lead tuberculosis eradication?
(Elsevier, 2018-10-30)
Article
Open Access25 years after the declaration of a Global Emergency by the World Health Organization, tuberculosis (TB) remains a major enemy to the humankind. During this period, much progress has been done to better understand its ... -
Cording mycobacterium tuberculosis bacilli have a key role in the progression towards active tuberculosis, which is stopped by previous immune response
(2020-02-08)
Article
Open AccessCording was the first virulence factor identified in Mycobacterium tuberculosis (Mtb). We aimed to ascertain its role in the induction of active tuberculosis (TB) in the mouse strain C3HeB/FeJ by testing the immunopathogenic ... -
Individual-based modeling of tuberculosis in a user-friendly interface: Understanding the epidemiological role of population heterogeneity in a city
(2016-01-01)
Article
Open Access© 2016 Prats, Montañola-Sales, Gilabert-Navarro, Valls, Casanovas-Garcia, Vilaplana, Cardona and López. For millennia tuberculosis (TB) has shown a successful strategy to survive, making it one of the world's deadliest ... -
Local inflammation, dissemination and coalescence of lesions are key for the progression toward active tuberculosis: the bubble model
(2016-02-02)
Article
Open AccessThe evolution of a tuberculosis (TB) infection toward active disease is driven by a combination of factors mostly related to the host response. -
Low dose aerosol fitness at the innate phase of murine infection better predicts virulence amongst clinical strains of mycobacterium tuberculosis
(2012-01-03)
Article
Open AccessBackground: Evaluation of a quick and easy model to determine the intrinsic ability of clinical strains to generate active TB has been set by assuming that this is linked to the fitness of Mycobacterium tuberculosis strain ... -
Modeling tuberculosis in Barcelona. A solution to speed-up agent-based simulations
(2015)
Conference report
Restricted access - publisher's policyTuberculosis remains one of the world’s deadliest infectious diseases. About one third of the world’s population is infected with tuberculosis bacteria. Understanding the dynamics of transmission at ... -
Modeling tuberculosis transmission in urban cities through agent-based simulation: the case of Barcelona
(Association for Computing Machinery (ACM), 2017)
Conference lecture
Open AccessTuberculosis remains one of the world’s deadliest infectious diseases. About one-third of the world’s population is infected with tuberculosis bacteria. Understanding the dynamics of transmission at different spatial ... -
Modelling the dynamics of tuberculosis lesions in a virtual lung: role of the bronchial tree in endogenous reinfection
(2020-05-20)
Article
Open AccessTuberculosis (TB) is an infectious disease that still causes more than 1.5 million deaths annually. The World Health Organization estimates that around 30% of the world’s population is latently infected. However, the ... -
The bubble model: mathematically explaining how active TB is possible
(2014)
Conference report
Open Access -
To achieve an earlier IFN-¿ response is not sufficient to control mycobacterium tuberculosis infection in mice
(2014-06-24)
Article
Open AccessThe temporo-spatial relationship between the three organs (lung, spleen and lymph node) involved during the initial stages of Mycobacterium tuberculosis infection has been poorly studied. As such, we performed an experimental ...
