Now showing items 1-11 of 11

    • A novel strategy to enhance interfacial adhesion in fiber-reinforced calcium phosphate cement 

      Gallinetti, Sara; Mestres, Gemma; Canal Barnils, Cristina; Persson, Cecilia; Ginebra Molins, Maria Pau (Elsevier, 2017-11-01)
      Article
      Open Access
      Covenantee:   Uppsala universitet
      Calcium phosphate cements (CPCs) are extensively used as synthetic bone grafts, but their poor toughness limits their use to non-load-bearing applications. Reinforcement through introduction of fibers and yarns has been ...
    • Brushite foams - the effect of Tween® 80 and Pluronic® F-127 on foam porosity and mechanical properties 

      Unosson, Johanna; Montufar Jiménez, Edgar Benjamin; Engqvist, Hakan; Ginebra Molins, Maria Pau; Persson, Cecilia (2015-01-23)
      Article
      Open Access
      Covenantee:   Uppsala universitet
      Resorbable calcium phosphate based bone void fillers should work as temporary templates for new bone formation. The incorporation of macropores with sizes of 100 -300 µm has been shown to increase the resorption rate of ...
    • Changes in the drug release pattern of fresh and set simvastatin-loaded brushite cement 

      Mestres Beà, Gemma; Kugiejko, Karol; Pastorino Carraz, David; Unosson, Johanna; Ohman, Caroline; Karlsson Ott, Marjam; Ginebra Molins, Maria Pau; Persson, Cecilia (2016-01-01)
      Article
      Open Access
      Covenantee:   Uppsala universitet
      Calcium phosphate cements are synthetic bone graft substitutes able to set at physiological conditions. They can be applied by minimally invasive surgery and can also be used as drug delivery systems. Consequently, the ...
    • Compressive, diametral tensile and biaxial flexural strength of cutting-edge calcium phosphate cements 

      Luo, Jun; Ajaxon, Ingrid; Ginebra Molins, Maria Pau; Engqvist, Hakan; Persson, Cecilia (Elsevier, 2016-07-01)
      Article
      Open Access
      Covenantee:   Uppsala universitet
      © 2016 The Authors. Calcium phosphate cements (CPCs) are widely used in bone repair. Currently there are two main types of CPCs, brushite and apatite. The aim of this project was to evaluate the mechanical properties of ...
    • Effect of calcium phosphate heparinization on the in vitro inflammatory response and osteoclastogenesis of human blood precursor cells 

      Díez Escudero, Anna; Torreggiani, E.; Pompo, Gemma di; Español Pons, Montserrat; Persson, Cecilia; Ciapetti, Gabriela; Baldini, Nicola; Ginebra Molins, Maria Pau (2019-01-01)
      Article
      Open Access
      Covenantee:   Istituto Ortopedico Rizzoli / Uppsala universitet / Università di Bologna / Institut de Bioenginyeria de Catalunya
      The immobilization of natural molecules on synthetic bone grafts stands as a strategy to enhance their biological interactions. During the early stages of healing, immune cells and osteoclasts (OC) modulate the inflammatory ...
    • Evaluation of a porosity measurement method for wet calcium phosphate cements 

      Ajaxon, Ingrid; Maazouz, Yassine; Ginebra Molins, Maria Pau; Ohman, Caroline; Persson, Cecilia (2015)
      Article
      Open Access
      Covenantee:   Uppsala universitet
      The porosity of a calcium phosphate cement is a key parameter as it affects several important properties of the cement. However, a successful, non-destructive porosity measurement method that does not include drying has ...
    • Impact of biomimicry in the design of osteoinductive bone substitutes: nanoscale matters 

      Barba Serrahima, Albert; Díez Escudero, Anna; Español Pons, Montserrat; Bonany Mariñosa, Mar; Sadowska, Joanna Maria; Guillem Martí, Jordi; Ohman, Caroline; Persson, Cecilia; Manzanares, Maria Cristina; Franch, Jordi; Ginebra Molins, Maria Pau (2019-01-01)
      Article
      Open Access
      Covenantee:   Universitat Autònoma de Barcelona / Uppsala universitet / Universitat de Barcelona. Departament de Patologia i Terapèutica Experimental / Institut de Bioenginyeria de Catalunya
      Bone apatite consists of carbonated calcium-deficient hydroxyapatite (CDHA) nanocrystals. Biomimetic routes allow fabricating synthetic bone grafts that mimic biological apatite. In this work, we explored the role of two ...
    • In vivo efficiency of antimicrobial inorganic bone grafts in osteomyelitis treatments 

      Mestres Beà, Gemma; Fernández Yague, Marc Antoni; Pastorino Carraz, David; Montufar Jiménez, Edgar Benjamin; Canal Barnils, Cristina; Manzanares Céspedes, Maria Cristina; Ginebra Molins, Maria Pau (Elsevier, 2019-04-01)
      Article
      Open Access
      Covenantee:   Uppsala universitet / Vysoké učení technické v Brně / Universitat de Barcelona. Facultat de Medicina i Ciències de la Salut / Institut de Bioenginyeria de Catalunya / Institut d'Investigació Biomèdica de Bellvitge
    • Porosity prediction of calcium phosphate cements based on chemical composition 

      Ohman, Caroline; Unusson, Johanna; Carlsson, Elin; Ginebra Molins, Maria Pau; Persson, Cecilia; Engqvist, Hakan (2015-07-01)
      Article
      Open Access
      Covenantee:   Uppsala universitet
      The porosity of calcium phosphate cements has an impact on several important parameters, such as strength, resorbability and bioactivity. A model to predict the porosity for biomedical cements would hence be a useful tool. ...
    • Reactive combinatorial synthesis and characterization of a gradient Ag-Ti oxide thin film with antibacterial properties 

      Unosson, Erik; Rodríguez Rius, Daniel; Welch, Ken; Engqvist, Hakan (2015-01-01)
      Article
      Open Access
      Covenantee:   Uppsala universitet
      The growing demand for orthopedic and dental implants has spurred researchers to develop multifunctional coatings, combining tissue integration with antibacterial features. A possible strategy to endow titanium (Ti) with ...
    • The effect of unsaturated fatty acid and triglyceride oil addition on the mechanical and antibacterial properties of acrylic bone cements 

      Persson, Cecilia; Robert, Elise; Carlsson, Elin; Robo, Celine; López-Gil Serra, Alejandro; Ginebra Molins, Maria Pau; Godoy Gallardo, María; Engqvist, Hakan (2015-09-01)
      Article
      Open Access
      Covenantee:   Uppsala universitet
      Acrylic bone cements have an elastic modulus several times higher than the surrounding trabecular bone. This has been hypothesized to contribute to certain clinical complications. There are indications that the addition ...