Now showing items 1-20 of 109

    • 3D printed hydrogel-based scaffolds for tissue regeneration 

      Perez Reyes, Daniel (Universitat Politècnica de Catalunya, 2019-07-08)
      Master thesis
      Open Access
      Tissue engineering is an emerging technology whose efforts are aimed towards repairing and regenerating injured tissues by developing bioactive scaffolds. Recently, scaffolds made of hydrogels have become interesting ...
    • 3D Printed porous polyamide macrocapsule combined with alginate microcapsules for safer cell-based therapies 

      Saenz del Burgo, Laura; Ciriza, Jesús; Espona Noguera, Albert; Illa, Xavi; Cabruja, Enric; Orive, Gorka; Hernández, Rosa Maria; Villa, Rosa; Pedraz, Jose Luiz; Álvarez, Mar (Nature, 2018-12)
      Article
      Open Access
      Cell microencapsulation is an attractive strategy for cell-based therapies that allows the implantation of genetically engineered cells and the continuous delivery of de novo produced therapeutic products. However, the ...
    • 3D printed scaffolds with core-shell structure for bone tissue engineering 

      García Masabet, Violeta del Valle (Universitat Politècnica de Catalunya, 2017-02-07)
      Master thesis
      Restricted access - author's decision
      Biomaterials with core-shell structure have been used as carriers for drug delivery applications and cell encapsulation, allowing several improvements in the field of tissue engineering. Although the usefulness of biomaterials ...
    • 3D silicon doped hydroxyapatite scaffolds decorated with Elastin-like Recombinamers for bone regenerative medicine 

      Vila, Mercedes; García, Ana; Girotti, Alessandra; Alonso, Matilde; Rodriguez Cabello, Jose Carlos; Gonzalez Vazquez, Arlyng; Planell Estany, Josep Anton; Engel López, Elisabeth; Buján, Julia; García Honduvilla, Natalio; Vallet Regi, Maria (2016-11-01)
      Article
      Open Access
      The current study reports on the manufacturing by rapid prototyping technique of three-dimensional (3D) scaffolds based on silicon substituted hydroxyapatite with Elastin-like Recombinamers (ELRs) functionalized surfaces. ...
    • 3D-printed alginate-peptide scaffolds for bone tissue engineering 

      Rosolek, Theo (Universitat Politècnica de Catalunya, 2020-02-20)
      Master thesis
      Open Access
      A main challenge of Tissue engineering is to create sustainable scaffolds that provide optimal biological properties to mimic the extracellular matrix(ECM). The aim of this project is to develop RGD modified alginate bioinks ...
    • A comprehensive evaluation of the activity and selectivity profile of ligands for RGD-binding integrins 

      Kapp, Tobias G.; Rechenmacher, Florian; Neubauer, Stefanie; Maltsev, Oleg V.; Cavalcanti-Adam, Elisabetta Ada; Zarka, Revital; Reuning, Ute; Notni, Johannes; Wester, Hans-Jürgen; Mas Moruno, Carlos; Spatz, Joachim; Geiger, Benjamin; Kessler, Horst (Macmillan Publishers, 2017-01-11)
      Article
      Open Access
      Covenantee:   Technische Universität München
      Integrins, a diverse class of heterodimeric cell surface receptors, are key regulators of cell structure and behaviour, affecting cell morphology, proliferation, survival and differentiation. Consequently, mutations in ...
    • A novel hybrid nanofibrous strategy to target progenitor cells for cost-effective in situ angiogenesis 

      Sachot, Nadège; Castaño Linares, Óscar; Oliveira, Hugo; Martí Muñoz, Joan; Roguska, Agata; Amedee, Joelle; Lewandowska, Malgorzata; Planell Estany, Josep Anton; Engel López, Elisabeth (Royal Society of Chemistry, 2016-11-02)
      Article
      Open Access
      Although the impact of composites based on Ti-doped calcium phosphate glasses is low compared with that of bioglass, they have been already shown to possess great potential for bone tissue engineering. Composites made of ...
    • Accelerated hardening of nanotextured 3D-plotted self-setting calcium phosphate inks 

      Raymond Llorens, Santiago; Maazouz, Yassine; Montufar Jiménez, Edgar Benjamin; Perez, Roman A.; González Arcos, Borja; Konka, Joanna Magdalena; Ginebra Molins, Maria Pau (Elsevier, 2018-01-01)
      Article
      Open Access
      Direct ink writing (DIW) techniques open up new possibilities for the fabrication of patient-specific bone grafts. Self-setting calcium phosphate inks, which harden at low temperature, allow obtaining nanostructured scaffolds ...
    • Apoptosis-like cell death induction and aberrant fibroblast properties in human incisional hernia fascia 

      Diaz, Ramon; Quiles Pérez, María Teresa; Guillem Martí, Jordi; López-Cano, Manuel; Huguet, Pere; Ramon-y-Cajal, Santiago; Reventós, Jaume; Armengol Carrasco, Manuel; Arbós Vilà, Maria Antonia (2011-06-06)
      Article
      Restricted access - publisher's policy
      Covenantee:   Hospital Universitari Vall d'Hebron
      Incisional hernia often occurs following laparotomy and can be a source of serious problems. Although there is evidence that a biological cause may underlie its development, the mechanistic link between the local tissue ...
    • avß3- or a5ß1-Integrin-Selective Peptidomimetics for Surface Coating 

      Mas Moruno, Carlos; Fraioli, Roberta; Rechenmacher, Florian; Neubauer, Stefanie; Kapp, Tobias G.; Kessler, Horst (2016-06-13)
      Article
      Open Access
      Covenantee:   Technische Universität München
      Engineering biomaterials with integrin-binding activity is a very powerful approach to promote cell adhesion, modulate cell behavior, and induce specific biological responses at the surface level. The aim of this Review ...
    • Brushite foams - the effect of Tween® 80 and Pluronic® F-127 on foam porosity and mechanical properties 

      Unosson, Johanna; Montufar Jiménez, Edgar Benjamin; Engqvist, Hakan; Ginebra Molins, Maria Pau; Persson, Cecilia (2015-01-23)
      Article
      Open Access
      Covenantee:   Uppsala universitet
      Resorbable calcium phosphate based bone void fillers should work as temporary templates for new bone formation. The incorporation of macropores with sizes of 100 -300 µm has been shown to increase the resorption rate of ...
    • BSA- and elastin-coated GO, but not collagen-coated GO, enhance the biological performance of alginate hydrogels 

      Raslan, Ahmed; Saenz del Burgo, Laura; Espona Noguera, Albert; Ochoa de Retana, Ana Maria; Sanjuán, María Luisa; Cañibano-Hernández, Alberto; Gálvez-Martín, Patriza; Ciriza, Jesús; Pedraz, Jose Luiz (2020-06-11)
      Article
      Open Access
      The use of embedded cells within alginate matrices is a developing technique with great clinical applications in cell-based therapies. However, one feature that needs additional investigation is the improvement of ...
    • Calcium phosphate cements: Optimization toward biodegradability 

      Lodoso Torrecilla, Irene; van den Beucken, Jeroen J.J.P.; Jansen, John A. (Elsevier, 2020-01-01)
      Article
      Open Access
      Synthetic calcium phosphate (CaP) ceramics represent the most widely used biomaterials for bone regenerative treatments due to their biological performance that is characterized by bioactivity and osteoconductive properties. ...
    • Caracterización de tejido óseo humano sometido a impacto con objeto punzante, arma blanca 

      García Vilana, Silvia (Universitat Politècnica de Catalunya, 2016-06-08)
      Master thesis
      Restricted access - confidentiality agreement
    • Cell viability and proliferation capability of long-term human dental pulp stem cell cultures 

      Martín Piedra, Miguel Angel; Garzón, Ingrid; Oliveira, Ana Celeste; Alfonso-Rodriguez, Camilo; Carriel, Victor; Scionti, Giuseppe; Alaminos, Miguel (2014-02)
      Article
      Open Access
      ackground aims Evaluation of cell viability is one of the most important steps of the quality control process for therapeutic use of cells. The aim of this study was to evaluate the long-term cell viability profile of ...
    • Chemically diverse multifunctional peptide platforms with antimicrobial and cell adhesive properties 

      Martín Gómez, Helena; Oliver Cervelló, Lluís; Buxadera Palomero, Judit; Ginebra Molins, Maria Pau; Mas Moruno, Carlos (2020-01-01)
      Article
      Restricted access - publisher's policy
      Bacterial infections and incomplete biomaterial integration are major problems that can lead to the failure of medical implants. However, simultaneously addressing these two issues remains a challenge. Here, we present a ...
    • Chondroinductive alginate-based hydrogels having graphene oxide for 3D printed scaffold fabrication 

      Olate Moya, Felipe; Mateos Timoneda, Miguel Ángel; Engel López, Elisabeth; Arens, Lukas; Wilhelm, Manfred; Palza, Humberto (2020-01-07)
      Article
      Open Access
      Scaffolds based on bioconjugated hydrogels are attractive for tissue engineering because they can partly mimic human tissue characteristics. For example, they can further increase their bioactivity with cells. However, ...
    • Comportamiento celular en andamios fabricados por rapid prototyping para la ingeniería tisular ósea 

      Puech, Laurent (Universitat Politècnica de Catalunya, 2013-02)
      Master thesis (pre-Bologna period)
      Open Access
      La fabricación de nuevos andamios biodegradables capaces de guiar y estimular la regeneración ósea es un objetivo de gran importancia en la ingeniería de los tejidos. En este sentido, se han desarrollado innovadoras ...
    • Computation of liquid phase migration occurring during the injection of cement materials 

      Todeschini, Yann (Universitat Politècnica de Catalunya, 2014-02)
      Master thesis (pre-Bologna period)
      Open Access
      Ceramic bone cements, mainly calcium phosphate based, represent an alternative to the polymeric cements used in Vertebroplasty. Unfortunately, calcium phosphate bone cements, which are made from mixing solid powder and ...
    • Customized interface biofunctionalization of decellularized extracellular matrix: towards enhanced endothelialization 

      Aubin, Hugh; Mas Moruno, Carlos; Iijima, Makoto; Schütterle, Nicolas; Steinbrink, Meike; Assmann, Alexander; Gil Mur, Francisco Javier; Lichtenberg, Artur; Pegueroles Neyra, Marta; Akhyari, Payam (2016)
      Article
      Restricted access - publisher's policy
      Covenantee:   Heinrich-Heine Universität Düsseldorf
      Interface biofunctionalization strategies try to enhance and control the interaction between implants and host organism. Decellularized extracellular matrix (dECM) is widely used as a platform for bioengineering of medical ...