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Browsing by Subject "Tissue engineering"

Now showing items 1-20 of 162

    • 3D printed hydrogel-based scaffolds for tissue regeneration 

      Perez Reyes, Daniel (Universitat Politècnica de Catalunya, 2019-07-08)
      Master thesis
      Open Access
      Tissue engineering is an emerging technology whose efforts are aimed towards repairing and regenerating injured tissues by developing bioactive scaffolds. Recently, scaffolds made of hydrogels have become interesting ...

    • 3D Printed porous polyamide macrocapsule combined with alginate microcapsules for safer cell-based therapies 

      Saenz del Burgo, Laura; Ciriza, Jesús; Espona Noguera, Albert; Illa, Xavi; Cabruja, Enric; Orive, Gorka; Hernández, Rosa Maria; Villa, Rosa; Pedraz, Jose Luiz; Álvarez, Mar (Nature, 2018-12)
      Article
      Open Access
      Cell microencapsulation is an attractive strategy for cell-based therapies that allows the implantation of genetically engineered cells and the continuous delivery of de novo produced therapeutic products. However, the ...

    • 3D printed scaffolds with core-shell structure for bone tissue engineering 

      García Masabet, Violeta del Valle (Universitat Politècnica de Catalunya, 2017-02-07)
      Master thesis
      Restricted access - author's decision
      Biomaterials with core-shell structure have been used as carriers for drug delivery applications and cell encapsulation, allowing several improvements in the field of tissue engineering. Although the usefulness of biomaterials ...

    • 3D silicon doped hydroxyapatite scaffolds decorated with Elastin-like Recombinamers for bone regenerative medicine 

      Vila, Mercedes; García, Ana; Girotti, Alessandra; Alonso, Matilde; Rodriguez Cabello, Jose Carlos; Gonzalez Vazquez, Arlyng; Planell Estany, Josep Anton; Engel López, Elisabeth; Buján, Julia; García Honduvilla, Natalio; Vallet Regi, Maria (2016-11-01)
      Article
      Open Access
      The current study reports on the manufacturing by rapid prototyping technique of three-dimensional (3D) scaffolds based on silicon substituted hydroxyapatite with Elastin-like Recombinamers (ELRs) functionalized surfaces. ...

    • 3D-printed alginate-peptide scaffolds for bone tissue engineering 

      Rosolek, Theo (Universitat Politècnica de Catalunya, 2020-02-20)
      Master thesis
      Open Access
      A main challenge of Tissue engineering is to create sustainable scaffolds that provide optimal biological properties to mimic the extracellular matrix(ECM). The aim of this project is to develop RGD modified alginate bioinks ...

    • A comprehensive evaluation of the activity and selectivity profile of ligands for RGD-binding integrins 

      Kapp, Tobias G.; Rechenmacher, Florian; Neubauer, Stefanie; Maltsev, Oleg V.; Cavalcanti-Adam, Elisabetta Ada; Zarka, Revital; Reuning, Ute; Notni, Johannes; Wester, Hans-Jürgen; Mas Moruno, Carlos; Spatz, Joachim; Geiger, Benjamin; Kessler, Horst (Macmillan Publishers, 2017-01-11)
      Article
      Open Access
      Covenantee:   Technische Universität München
      Integrins, a diverse class of heterodimeric cell surface receptors, are key regulators of cell structure and behaviour, affecting cell morphology, proliferation, survival and differentiation. Consequently, mutations in ...

    • A computational model for early cell spreading, migration, and competing taxis 

      Betorz Llobet, Joel; Bokil, Gaurav Rajendra; Deshpande, Shreyas M.; Kulkarnic, Shardool; Araya Matilla, Daniel Rolando; Venturini, Chiara; Sáez Viñas, Pablo (Elsevier, 2023-10)
      Article
      Open Access
      Cell motility represents one of the most fundamental functions in life such as organ development or tissue regeneration and diseases such as cancer. Here, we derived a computational model of cell motility that incorporates ...

    • A novel hybrid nanofibrous strategy to target progenitor cells for cost-effective in situ angiogenesis 

      Sachot, Nadège; Castaño Linares, Óscar; Oliveira, Hugo; Martí Muñoz, Joan; Roguska, Agata; Amedee, Joelle; Lewandowska, Malgorzata; Planell Estany, Josep Anton; Engel López, Elisabeth (Royal Society of Chemistry, 2016-11-02)
      Article
      Open Access
      Although the impact of composites based on Ti-doped calcium phosphate glasses is low compared with that of bioglass, they have been already shown to possess great potential for bone tissue engineering. Composites made of ...

    • Accelerated hardening of nanotextured 3D-plotted self-setting calcium phosphate inks 

      Raymond Llorens, Santiago; Maazouz, Yassine; Montufar Jiménez, Edgar Benjamin; Perez, Roman A.; González Arcos, Borja; Konka, Joanna Magdalena; Ginebra Molins, Maria Pau (Elsevier, 2018-01-01)
      Article
      Open Access
      Direct ink writing (DIW) techniques open up new possibilities for the fabrication of patient-specific bone grafts. Self-setting calcium phosphate inks, which harden at low temperature, allow obtaining nanostructured scaffolds ...

    • An explicit total Lagrangian Fragile Points Method for finite deformation of hyperelastic materials 

      Mountris, Konstantinos A.; Li, Mingjing; Schilling, Richard; Dong, Leiting; Atluri, Satya N.; Casals Gelpí, Alicia; Wurdemann, Helge (2023-06)
      Article
      Open Access
      We present a novel meshless algorithm based on the Fragile Points Method (FPM) for hyperelastic materials undergoing finite deformation. In contrast to mesh-based methods, where mesh distortion may pose numerical challenges. ...

    • Antibacterial approaches in tissue engineering using metal ions and nanoparticles: From mechanisms to applications 

      Godoy Gallardo, Maria; Eckhard, Ulrich; Delgado Garoña, Luis María; de Roo Puente, Yolanda J.D.; Hoyos Nogués, Mireia; Gil Mur, Francisco Javier; Pérez Antoñanzas, Román (2021-12)
      Article
      Open Access
      Bacterial infection of implanted scaffolds may have fatal consequences and, in combination with the emergence of multidrug bacterial resistance, the development of advanced antibacterial biomaterials and constructs is of ...

    • Apoptosis-like cell death induction and aberrant fibroblast properties in human incisional hernia fascia 

      Diaz, Ramon; Quiles Pérez, María Teresa; Guillem Martí, Jordi; López-Cano, Manuel; Huguet, Pere; Ramon-y-Cajal, Santiago; Reventós, Jaume; Armengol Carrasco, Manuel; Arbós Vilà, Maria Antonia (2011-06-06)
      Article
      Restricted access - publisher's policy
      Covenantee:   Hospital Universitari Vall d'Hebron
      Incisional hernia often occurs following laparotomy and can be a source of serious problems. Although there is evidence that a biological cause may underlie its development, the mechanistic link between the local tissue ...

    • Arrested coalescence: a tool to explore tissue rheology 

      Samatas, Sotiris; Planasdemunt Hospital, Martí; Oriola Santandreu, David (Multidisciplinary Digital Publishing Institute (MDPI), 2024-11-28)
      Article
      Open Access
      Tissue spheroids are self-organised 3D cellular aggregates that serve as a versatile platform in tissue engineering. While numerous high-throughput methods exist to characterise the cellular function of tissue spheroids, ...

    • avß3- or a5ß1-Integrin-Selective Peptidomimetics for Surface Coating 

      Mas Moruno, Carlos; Fraioli, Roberta; Rechenmacher, Florian; Neubauer, Stefanie; Kapp, Tobias G.; Kessler, Horst (2016-06-13)
      Article
      Open Access
      Covenantee:   Technische Universität München
      Engineering biomaterials with integrin-binding activity is a very powerful approach to promote cell adhesion, modulate cell behavior, and induce specific biological responses at the surface level. The aim of this Review ...

    • Bastides per impressió 3D com a sistema d'alliberament de ions 

      Segura Romero, Eulàlia (Universitat Politècnica de Catalunya, 2022-07-05)
      Bachelor thesis
      Restricted access - confidentiality agreement
      Covenantee:   Institut de Bioenginyeria de Catalunya
      En aquest treball, es fa un estudi sobre la complexitat d’imprimir estructures en 3D amb polisacàrids tous, com és el quitosà, mitjançant una pressió pneumàtica i a temperatura ambient. Es porta a terme la caracterització ...

    • Brain tissue mechanics is governed by microscale relations of the tissue constituents 

      Sáez Viñas, Pablo; Borau Zamora, Carlos; Antonovaite, Nelda; Franze, Kristian (Elsevier, 2023-10-01)
      Article
      Open Access
      Local mechanical tissue properties are a critical regulator of cell function in the central nervous system (CNS) during development and disorder. However, we still don't fully understand how the mechanical properties of ...

    • Brushite foams - the effect of Tween® 80 and Pluronic® F-127 on foam porosity and mechanical properties 

      Unosson, Johanna; Montufar Jiménez, Edgar Benjamin; Engqvist, Hakan; Ginebra Molins, Maria Pau; Persson, Cecilia (2015-01-23)
      Article
      Open Access
      Covenantee:   Uppsala universitet
      Resorbable calcium phosphate based bone void fillers should work as temporary templates for new bone formation. The incorporation of macropores with sizes of 100 -300 µm has been shown to increase the resorption rate of ...

    • BSA- and elastin-coated GO, but not collagen-coated GO, enhance the biological performance of alginate hydrogels 

      Raslan, Ahmed; Saenz del Burgo, Laura; Espona Noguera, Albert; Ochoa de Retana, Ana Maria; Sanjuán, María Luisa; Cañibano-Hernández, Alberto; Gálvez-Martín, Patriza; Ciriza, Jesús; Pedraz, Jose Luiz (2020-06-11)
      Article
      Open Access
      The use of embedded cells within alginate matrices is a developing technique with great clinical applications in cell-based therapies. However, one feature that needs additional investigation is the improvement of ...

    • Calcium phosphate cements: Optimization toward biodegradability 

      Lodoso Torrecilla, Irene; van den Beucken, Jeroen J.J.P.; Jansen, John A. (Elsevier, 2020-01-01)
      Article
      Open Access
      Synthetic calcium phosphate (CaP) ceramics represent the most widely used biomaterials for bone regenerative treatments due to their biological performance that is characterized by bioactivity and osteoconductive properties. ...

    • Caracterización de tejido óseo humano sometido a impacto con objeto punzante, arma blanca 

      García Vilana, Silvia (Universitat Politècnica de Catalunya, 2016-06-08)
      Master thesis
      Restricted access - confidentiality agreement