Browsing by Author "Tamborero, Silvia"

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    • Design of a minimized cyclic tetrapeptide that neutralizes bacterial endotoxins 

      Mora, Puig; Mas Moruno, Carlos; Tamborero, Silvia; Cruz, Luis Javier; Pérez-Payá, Enrique; Albericio, Fernando (2006)
      Article
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      Septic shock is a leading cause of mortality in intensive care patients, and no specific drugs are as yet available for its treatment. Therefore, new leads ar e required in order to increase the numbe r of active ...

    • Tiratricol neutralizes bacterial endotoxins and reduces lipopolysaccharide-induced TNF-alpha production in the cell 

      Cascales, L.; Mas Moruno, Carlos; Tamborero, Silvia; Aceña, J.L.; Sanz, J.F.; Fustero, S.; Cruz, Luis Javier; Albericio, Fernando; Mora, P.; Pérez-Payá, Enrique (2008)
      Article
      Restricted access - publisher's policy
      The screening of a commercially available library of compounds has proved a successful strategy for the identification of a lead compound in a drug discovery programme. Here, we analysed 880 off-patent drugs, which initially ...