Browsing by Author "Schütz, Helmut"

Now showing items 1-1 of 1

An iterative method to protect the type I error rate in bioequivalence studies under two-stage adaptive 2×2 crossover designs

Molins Lleonart, Eduard; Labes, Detlew; Schütz, Helmut; Cobo Valeri, Erik; Ocaña Rebull, Jordi (2021-01)
Article
Open Access
Bioequivalence studies are the pivotal clinical trials submitted to regulatory agen- cies to support the marketing applications of generic drug products. Average bioequivalence (ABE) is used to determine whether the mean ...