Browsing by Author "Saus, Ester"
Now showing items 1-11 of 11
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A mouse model suggests that heart failure and its common comorbidity sleep fragmentation have no synergistic impacts on the gut microbiome
Khannous Lleiffe, Olfat; Willis, Jesse R.; Saus, Ester; Cabrera Aguilera, Ignacio; Almendros, Isaac; Farré, Ramon; Gozal, David; Farré, Nuria; Gabaldón, Toni (MDPI, 2021)
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Open AccessHeart failure (HF) is a common condition associated with a high rate of hospitalizations and adverse outcomes. HF is characterized by impairments of either the cardiac ventricular filling, ejection of blood capacity or ... -
Chromosome-level assemblies from diverse clades reveal limited structural and gene content variation in the genome of Candida glabrata
Marcet Houben, Marina; Alvarado, María; Ksiezopolska, Ewa; Saus, Ester; de Groot, Piet W. J.; Gabaldón, Toni (BioMed Central (BMC), 2022)
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Open AccessBackground Candida glabrata is an opportunistic yeast pathogen thought to have a large genetic and phenotypic diversity and a highly plastic genome. However, the lack of chromosome-level genome assemblies representing ... -
Citizen-science reveals changes in the oral microbiome in Spain through age and lifestyle factors
Willis, Jesse R.; Saus, Ester; Iraola Guzmán, Susana; Ksiezopolska, Ewa; Cozzuto, Luca; Gabaldón, Toni (Nature Research, 2022)
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Open AccessThe relevance of the human oral microbiome to our understanding of human health has grown in recent years as microbiome studies continue to develop. Given the links of the oral cavity with the digestive, respiratory and ... -
Discovery and validation of clinically relevant long non-coding RNAs in colorectal cancer
Snyder, Madison; Iraola Guzmán, Susana; Saus, Ester; Gabaldón, Toni (MDPI, 2022-08)
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Open AccessColorectal cancer (CRC) is the third most prevalent cancer worldwide, with nearly two million newly diagnosed cases each year. The survival of patients with CRC greatly depends on the cancer stage at the time of diagnosis, ... -
Extreme diversification driven by parallel events of massive loss of heterozygosity in the hybrid lineage of Candida albicans
Mixão, Verónica; Saus, Ester; Boekhout, Teun; Gabaldon, Toni (Oxford University Press, 2021-02)
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Open AccessCandida albicans is the most commonly reported species causing candidiasis. The taxonomic classification of C. albicans and related lineages is controversial, with Candida africana (syn. C. albicans var. africana) and ... -
Genome analysis of Candida subhashii reveals its hybrid nature and dual mitochondrial genome conformations
Mixão, Verónica; Hegedűsová, Eva; Saus, Ester; Pryszcz, Leszek P; Cillingová, Andrea; Nosek, Jozef; Gabaldón, Toni (Oxford University Press, 2021-06)
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Open AccessCandida subhashii belongs to the CUG-Ser clade, a group of phylogenetically closely related yeast species that includes some human opportunistic pathogens, such as Candida albicans. Despite being present in the environment, ... -
Genome analysis of five recently described species of the CUG-Ser clade uncovers Candida theae as a new hybrid lineage with pathogenic potential in the Candida parapsilosis species complex
Mixão, Verónica; Olmo, Valentina del; Hegedűsová, Eva; Saus, Ester; Pryszcz, Leszek; Cillingová, Andrea; Nosek, Jozef; Gabaldón, Toni (Oxford University Press, 2022-04)
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Open AccessCandida parapsilosis species complex comprises three important pathogenic species: Candida parapsilosis sensu stricto, Candida orthopsilosis and Candida metapsilosis. The majority of C. orthopsilosis and all C. metapsilosis ... -
Genome Assemblies of Two Rare Opportunistic Yeast Pathogens: Diutina rugosa (syn. Candida rugosa) and Trichomonascus ciferrii (syn. Candida ciferrii)
Mixão, Verónica; Saus, Ester; Perez Hansen, Antonio; Lass Florl, Cornelia; Gabaldon, Toni (Genetics Society of America (GSA), 2019)
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Open AccessInfections caused by opportunistic yeast pathogens have increased over the last years. These infections can be originated by a large number of diverse yeast species of varying incidence, and with distinct clinically relevant ... -
Oral microbiome in down syndrome and its implications on oral health
Willis, Jesse R; Iraola-Guzmán, Susana; Saus, Ester; Ksiezopolska, Ewa; Cozzuto, Luca; Bejarano, Luis A; Alloza-Trabado, Miriam; Puig-Sola, Anna; Blanco, Andrea; Broglio, Elisabetta; Carolis, Carlo; Hecht, Jochen; Ponomarenko, Julia; Gabaldon, Toni (Taylor and Francis, 2020)
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Open AccessIntroduction: The oral cavity harbors an abundant and diverse microbial community (i.e. the microbiome), whose composition and roles in health and disease have been the focus of intense research. Down syndrome (DS) is ... -
Structural characterization of NORAD reveals a stabilizing role of spacers and two new repeat units
Chorostecki, Uciel; Saus, Ester; Gabaldón, Toni (Elsevier, 2021)
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Open AccessLong non-coding RNAs (lncRNAs) can perform a variety of key cellular functions by interacting with proteins and other RNAs. Recent studies have shown that the functions of lncRNAS are largely mediated by their structures. ... -
The transcriptional aftermath in two independently formed hybrids of the opportunistic pathogen candida orthopsilosis
Hovhannisyan, Hrant; Saus, Ester; Ksiezopolska, Ewa; Gabaldón, Toni (American Society for Microbiology, 2020)
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Open AccessInterspecific hybridization can drive evolutionary adaptation to novel environments. The Saccharomycotina clade of budding yeasts includes many hybrid lineages, and hybridization has been proposed as a source for new ...