Now showing items 1-4 of 4

    • Computationally driven rational design of substrate promiscuity on serine ester hydrolases 

      Roda, Sergi; Fernandez Lopez, Laura; Cañadas, Rubén; Santiago, Gerard; Ferrer, Manuel; Guallar, Victor (American Chemical Society, 2021)
      Article
      Open Access
      Enzymes with a broad substrate specificity are of great interest both at the basic and applied level. Understanding the main parameters that make an enzyme substrate ambiguous could be thus important not only for their ...
    • Mapping enzyme-substrate interactions: its potential to study the mechanism of enzymes 

      Roda, Sergi; Santiago, Gerard; Guallar, Victor (Academic Press Inc., 2020-09)
      Part of book or chapter of book
      Open Access
      With the increase of the need to use more sustainable processes for the industry in our society, the modeling of enzymes has become crucial to fully comprehend their mechanism of action and use this knowledge to enhance ...
    • Metagenomic mining for esterases in the microbial community of Los Rueldos acid mine drainage formation 

      Vidal, Paula; Martínez Martínez, Mónica; Fernandez Lopez, Laura; Roda, Sergi; Méndez García, Celia; Golyshina, Olga V.; Guallar, Victor; Pelaez, Ana Isabel; Ferrer, Manuel (Frontiers Media, 2022-05)
      Article
      Open Access
      Acid mine drainage (AMD) systems are extremely acidic and are metal-rich formations inhabited by relatively low-complexity communities of acidophiles whose enzymes remain mostly uncharacterized. Indeed, enzymes from only ...
    • Structural-Based Modeling in Protein Engineering. A Must Do 

      Roda, Sergi; Robles -Martin, Ana; Xiang, Ruite; Kazemi, Masoud; Guallar, Victor (American Chemical Society, 2021)
      Article
      Open Access
      Biotechnological solutions will be a key aspect in our immediate future society, where optimized enzymatic processes through enzyme engineering might be an important solution for waste transformation, clean energy production, ...