Now showing items 1-2 of 2

    • Cold plasma and inhibition of STAT3 selectively target tumorigenicity in osteosarcoma 

      Tornin Cavielles, Juan; Mateu Sanz, Miguel; Rey, Veronica; Murillo, Dzohara; Huergo García, Carmen; Gallego, Borja; Rodríguez, Aida; Rodríguez, René; Canal Barnils, Cristina (2023-06-01)
      Article
      Open Access
      Covenantee:   Institut de Recerca Sant Joan de Déu / Hospital Universitario Central de Asturias / Instituto Universitario de Oncología del Principado de Asturias / CIBERONC. Centro de Investigación Biomédica en Red. Cáncer
      Osteosarcoma (OS) is a malignant type of bone cancer that arises in periods of increased bone formation. Curative strategies for these types of tumors have remained essentially unchanged for decades and the overall survival ...
    • The multikinase inhibitor EC‐70124 synergistically increased the antitumor activity of doxorubicin in sarcomas 

      Estupiñan, Oscar; Santos, Laura; Rodriguez, Aida; Fernandez-Nevado, Lucia; Costales, Paula; Perez‐Escuredo, Jhudit; Hermosilla, Maria Ana; Oro, Patricia; Rey, Veronica; Tornin Cavielles, Juan; Allonca, Eva; Fernandez Garcia, Maria Teresa; Alvarez Fernandez, Carlos; Braña, Alejandro; Astudillo, Aurora; Menendez, Sofia T.; Moris, Francisco; Rodriguez, Rene (Wiley (John Wiley & Sons), 2018-12-21)
      Article
      Open Access
      Cytotoxic drugs like doxorubicin remain as the most utilized agents in sarcoma treatment. However, advanced sarcomas are often resistant, thus stressing the need for new therapies aimed to overcome this resistance. Multikinase ...